basal cell carcinoma of the head and neck基底细胞癌的头部和颈部.pdfVIP

Hindawi Publishing Corporation Journal of Skin Cancer Volume 2011, Article ID 496910, 9 pages doi:10.1155/2011/496910 Review Article Basal Cell Carcinoma of the Head and Neck Masahiro Nakayama,1 Keiji Tabuchi,1 Yasuhiro Nakamura,2 and Akira Hara1 1 Department of Otolaryngology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan 2 Department of Dermatology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan Correspondence should be addressed to Keiji Tabuchi, ktabuchi@md.tsukuba.ac.jp Received 30 June 2010; Revised 17 August 2010; Accepted 19 October 2010 Academic Editor: M. Lebwohl Copyright © 2011 Masahiro Nakayama et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Basal cell carcinoma (BCC) is a malignant neoplasm derived from nonkeratinizing cells that originate from the basal layer of the epidermis and is the most frequent type of skin cancer in humans, with cumulative exposure to ultraviolet radiation as an important risk factor. BCC occurs most frequently at sun-exposed sites, with the head and neck being common areas. Tumors can be classified as nodular, superficial, morpheaform, infiltrating, metatypic, and fibroepithelioma of Pinkus. Several treatment options such as surgical excision and nonsurgical procedures are available. The choice of treatment should be determined based on the histological subtype of a lesion, cost, its size and location, patient age, medical condition of the patient, treatment availability, and the patient’s wishes. The aim of