diabetic retinopathy grading by digital curvelet transform糖尿病性视网膜病变评分由数字曲波变换.pdfVIP

Hindawi Publishing Corporation Computational and Mathematical Methods in Medicine Volume 2012, Article ID 761901, 11 pages doi:10.1155/2012/761901 Research Article Diabetic Retinopathy Grading by Digital Curvelet Transform Shirin Hajeb Mohammad Alipour,1 Hossein Rabbani,1 and Mohammad Reza Akhlaghi2 1 Biomedical Engineering Department, Medical Image Signal Processing Research Center, Isfahan University of Medical Sciences, Isfahan Iran 2 Ophthalmology Department, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran Correspondence should be addressed to Hossein Rabbani, h rabbani@med.mui.ac.ir Received 24 May 2012; Accepted 30 July 2012 Academic Editor: Jacek Waniewski Copyright © 2012 Shirin Hajeb Mohammad Alipour et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. One of the major complications of diabetes is diabetic retinopathy. As manual analysis and diagnosis of large amount of images are time consuming, automatic detection and grading of diabetic retinopathy are desired. In this paper, we use fundus fluorescein angiography and color fundus images simultaneously, extract 6 features employing curvelet transform, and feed them to support vector machine in order to determine diabetic retinopathy severity stages. These features are area of blood vessels, area, regularity of foveal avascular zone, and the number of micro-aneurisms therein, total number of micro-aneurisms, and area of exudates. In order to extract exudates and vessels, we respectively modify curvelet coefficients of color fundus images and angiograms. The end points of extracted vessels in predefin