exposure of the main italian river basin to pharmaceuticals接触的主要意大利流域药品.pdfVIP

Hindawi Publishing Corporation Journal of Toxicology Volume 2011, Article ID 989270, 11 pages doi:10.1155/2011/989270 Research Article Exposure of the Main Italian River Basin to Pharmaceuticals Federico Ferrari,1, 2 Agata Gallipoli,1 Matteo Balderacchi,1 Maria M. Ulaszewska,1 Ettore Capri,1 and Marco Trevisan1 1 Istituto di Chimica Agraria ed Ambientale, Universita Cattolica del Sacro Cuore, 29122 Piacenza, Italy ` 2 AEIFORIA Spin-Off Company dell’ Universita Cattolica del Sacro Cuore, 43036 Fidenza, 43036 Fidenza, Italy ` Correspondence should be addressed to Marco Trevisan, marco.trevisan@unicatt.it Received 1 April 2011; Accepted 17 June 2011 Academic Editor: Mahfuzar Rahman Copyright © 2011 Federico Ferrari et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. This study give a preliminary survey of pharmaceutical contamination and accumulation in surface waters and sediments along the river Po basin (74,000 km2 , the largest in Italy), a strategic region for the Italian economy: it collects sewage from a vast ` industrialized area of Italy (Autorita di Baciono del fiume Po, 2006, 2009). 10 pharmaceuticals (atenolol, propanolol, metoprolol, nimesulide, furosemide, carbamazepine, ranitidine, metronidazole, paracetamol, and atorvastatin) from several therapeutic classes were searched in 54 sampling points along the river Po from the source to the delta, and at the mouth of its major effluents. In water samples were f