association of c-reactive protein, interleukin-1 receptor antagonist and adiponectin with the metabolic syndrome协会的c反应蛋白,脂联素受体拮抗剂及代谢综合征.pdfVIP

Hindawi Publishing Corporation Mediators of Inflammation Volume 2007, Article ID 93573, 8 pages doi:10.1155/2007/93573 Research Article Association of C-Reactive Protein, Interleukin-1 Receptor Antagonist and Adiponectin with the Metabolic Syndrome Juha Saltevo,1 Mauno Vanhala,2, 3 Hannu Kautiainen,4 Esko Kumpusalo,5, 6 and Markku Laakso7 1 Department of Internal Medicine, Central Hospital of Middle Finland, 40620 Jyvaskyla, Finland ¨ ¨ 2 Department of General Medicine, Central Hospital of Middle Finland, 40620 Jyvaskyla, Finland ¨ ¨ 3 Laukaa Health Center, 41341 Laukaa, Finland 4 ¨ Medcare Foundation, 44100 Aanekoski, Finland ¨ 5 Department of Public Health and Clinical Nutrition, University of Kuopio, 70211 Kuopio, Finland 6 Unit of General Practice, Kuopio University Hospital, 70211 Kuopio, Finland 7 Department of Medicine, University of Kuopio, 70211 Kuopio, Finland Correspondence should be addressed to Juha Saltevo, juha.saltevo@ksshp.fi Received 6 July 2007; Accepted 29 August 2007 This Finnish population-based study, mean age 46 years, evaluates the association of high-sensitivity C-reactive protein (hs-CRP), interleukin-1 receptor antagonist (IL-1Ra), and adiponectin with the NCEP and IDF definitions of metabolic syndrome (MetS). Adiponectin levels were higher, hs-CRP and IL-1Ra levels lower in subjects without MetS compared to subjects with MetS. If MetS was present according to both IDF and NCEP criteria, BMI, waist, triglycerides, hs-CRP, and IL-1Ra were significantly higher