concurrent fdg avid nasopharyngeal lesion and generalized lymphadenopathy on pet-ct imaging is indicative of lymphoma in patients with hiv infection并发fdg狂热的鼻咽病变的磁共振成像的象征和广泛性淋巴结病淋巴瘤患者的艾滋病毒感染.pdfVIP

Hindawi Publishing Corporation AIDS Research and Treatment Volume 2012, Article ID 764291, 6 pages doi:10.1155/2012/764291 Clinical Study Concurrent FDG Avid Nasopharyngeal Lesion and Generalized Lymphadenopathy on PET-CT Imaging Is Indicative of Lymphoma in Patients with HIV Infection Yiyan Liu Nuclear Medicine Service, Department of Radiology, New Jersey Medical School, 150 Bergen Street, H141, Newark, NJ 07103, USA Correspondence should be addressed to Yiyan Liu, liuyl@ Received 18 May 2012; Revised 29 July 2012; Accepted 9 August 2012 Academic Editor: D. A. Katzenstein Copyright © 2012 Yiyan Liu. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Patients with HIV infection often have generalized lymphadenopathy and/or other lymphoid proliferation and are at significantly increased risk for lymphoma. This study retrospectively evaluated the diagnostic value of concurrent nasopharyngeal lesion and lymphadenopathy on positron emission tomography-computed tomography (PET-CT) with fluorine-18 fluorodeoxyglucose (FDG PET-CT) imaging. The eligible cases were from patients with HIV infection and lymphadenopathy and referred for FDG PET-CT to evaluate lymphoma or other malignancies prior to pathological investigation. FDG PET-CT images and interpretation reports were correlated with clinical information and pathological diagnoses. Among 22 eligible patients, FDG avid nasopha- ryngeal lesions were incidentally noted in 7 on PET-CT imaging, and all had lymphomas diagnosed with subsequent biopsies (6 diffuse large B-cell lymphomas and 1 Hodgkin’s lymphoma). In the remaining 15 patients with adenopathy but no vis