dynamic spatial discrimination maps of discriminative activation between different tasks based on support vector machines动态空间歧视之间的区别的激活地图基于支持向量机的不同的任务.pdfVIP

Applied Mathematics , 2011, 2, 85-92 doi:10.4236/am.2011.21010 Published Online January 2011 (http://www.SciRP.org/journal/am) Dynamic Spatial Discrimination Maps of Discriminative Activation between Different Tasks Based on Support Vector Machines Guangxin Huang1,2, Huafu Chen1*, Feng Yin3 1 Key laboratory for Neuroinformation of Ministry of Education, School of Life Science and Technology, School of Mathematics Science, University of Electronic Science and Technology of China, Chengdu, China 2School of Management Science, Chengdu University of Technology, Chengdu, China 3School of Science, Sichuan University of Science and Engineering, Zigong, China E-mail : huangx@, chenhf@ Received October 19, 2010; revised November 16, 2010; accepted November 19, 2010 Abstract As a set of supervised pattern recognition methods, support vector machines (SVMs) have been successfully applied to functional magnetic resonance imaging (fMRI) field, but few studies have focused on visualizing discriminative regions of whole brain between different cognitive tasks dynamically. This paper presents a SVM-based method for visualizing dynamically discriminative activation of whole-brain voxels between two kinds of tasks without any contrast. Our method provides a series of dynamic spatial discrimination maps (DSDMs), representing the temporal evolution of discriminative brain activation during a duty cycle and de- scribing how the discriminating information changes over the duty cycle. The proposed method was applied to investigate discriminative brain functional activations of whole brain voxels dynamically based on a hand-motor task experiment. A set of DSDMs between left hand movement and right hand movement were