the effect of 50？000 iu vitamin a with bcg vaccine at birth on growth in the first year of life50的影响 000 iu维生素a与卡介苗在出生在生命的第一年增长.pdfVIP

Hindawi Publishing Corporation Journal of Tropical Medicine Volume 2011, Article ID 570170, 9 pages doi:10.1155/2011/570170 Research Article The Effect of 50 000 IU Vitamin A with BCG Vaccine at Birth on Growth in the First Year of Life Ane Bærent Fisker,1, 2, 3 Christine Stabell Benn,1, 2 Birgitte Rode Diness,1 Cesario Martins,1 Amabelia Rodrigues,1 Peter Aaby,1, 2 and Bo Martin Bibby3 1 Bandim Health Project, Indepth Network, Apartado 861, 1004 Bissau, Guinea-Bissau 2 Bandim Health Project, Statens Serum Institut, Ørestads Boulevard 5, 2300 Copenhagen S, Denmark 3 ˚ ˚ Department of Biostatistics, Institute of Public Health, University of Arhus, Bartholins Alle 2, 8000 Arhus C, Denmark Correspondence should be addressed to Ane Bærent Fisker, a.fisker@ Received 23 March 2011; Revised 2 July 2011; Accepted 6 July 2011 Academic Editor: Sabra Klein Copyright © 2011 Ane Bærent Fisker et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Vitamin A supplements may interact with diphtheria-tetanus-pertussis (DTP) vaccine causing increased female mortality. In a randomised trial of neonatal vitamin A supplementation (VAS), we examined growth during the first year of life in 808 children, pursuing the hypothesis that a negative interaction between VAS and DTP in girls would be reflected in growth. Length and weight were measured at 6 weekly visits and WHO-growth-reference z-scores derived. Neonatal VAS had no effect on anthropometric measures at 12 months, but may interact sex differentially with routine vac