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Hindawi Publishing Corporation Sarcoma Volume 2012, Article ID 953602, 10 pages doi:10.1155/2012/953602 Clinical Study Should Aggressive Surgical Local Control Be Attempted in All Patients with Metastatic or Pelvic Ewing’s Sarcoma? Steven W. Thorpe,1 Kurt R. Weiss,2 Mark A. Goodman,2 Alma E. Heyl,3 and Richard L. McGough4 1 Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, 3471 Fifth Avenue, Suite 1010, Pittsburgh, PA 15213, USA 2 Division of Musculoskeletal Oncology, Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, UPMC Shadyside Medical Building, 5200 Centre Avenue, Suite 415, Pittsburgh, PA 15232, USA 3 Division of Musculoskeletal Oncology and Adult Reconstruction, Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, UPMC Shadyside Medical Building, 5200 Centre Avenue, Suite 415, Pittsburgh, PA 15232, USA 4 Division of Musculoskeletal Oncology, Departments of Orthopaedic Surgery and Surgery, UPCI Sarcoma Service, University of Pittsburgh Medical Center, UPMC Shadyside Medical Building, 5200 Centre Avenue, Suite 415, Pittsburgh, PA 15232, USA Correspondence should be addressed to Kurt R. Weiss, weisskr@ Received 15 August 2011; Revised 23 October 2011; Accepted 18 November 2011 Academic Editor: Ajay Puri Copyright © 2012 Steven W. Thorpe et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In previous reports, patients with Ewing’s sarcoma received radiation therapy (XRT) for definitive local control because metastatic disease and pelvic location were thought to preclude aggressive local