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Hindawi Publishing Corporation Gastroenterology Research and Practice Volume 2012, Article ID 750750, 6 pages doi:10.1155/2012/750750 Clinical Study Silicea Gastrointestinal Gel Improves Gastrointestinal Disorders: A Non-Controlled, Pilot Clinical Study B. Uehleke,1, 2, 3 M. Ortiz,1, 4 and R. Stange1 1 Department for Natural Medicine, Charite-Universitatsmedizin Berlin, Immanuel Hospital, 14109 Berlin, Germany ´ ¨ 2 Institute of Complementary Medicine, University Hospital Zurich, 8091 Zurich, Switzerland ¨ ¨ 3 University of Health Sport, 10367 Berlin, Germany 4 Institute for Social Medicine, Epidemiology and Health Economics, Charite University Medical Center, 10098 Berlin, Germany ´ Correspondence should be addressed to B. Uehleke, b.uehleke@immanuel.de Received 29 June 2011; Revised 18 October 2011; Accepted 18 October 2011 Academic Editor: C. M. Wilcox Copyright © 2012 B. Uehleke et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Aim . To investigate efficacy and tolerability of Silicea Gastrointestinal Gel in patients with gastrointestinal disorders. Methods. Open, prospective pivotal phase IV study with oral Silicea Gastrointestinal Gel over 6 weeks. Symptom score was part 1 of the Nepean Dyspepsia Index: 15 questions addressing intensity, frequency and impact of upper abdominal symptoms. 10 lower abdominal symptoms were asked analogously. A responder showed reduction