simple cystatin c formula for estimation of glomerular filtration rate in overweight patients with diabetes mellitus type 2 and chronic kidney disease简单的半胱氨酸蛋白酶抑制物c公式估算的肾小球滤过率在超重2型糖尿病患者和慢性肾脏疾病.pdfVIP

Hindawi Publishing Corporation Experimental Diabetes Research Volume 2012, Article ID 179849, 8 pages doi:10.1155/2012/179849 Clinical Study Simple Cystatin C Formula for Estimation of Glomerular Filtration Rate in Overweight Patients with Diabetes Mellitus Type 2 and Chronic Kidney Disease 1 1 1 ˇ 2 Sebastjan Bevc, Radovan Hojs, Robert Ekart, Matej Zavrsnik, Maksimiljan Gorenjak,3 and Ludvik Puklavec4 1 Department of Nephrology, Clinic of Internal Medicine, University Medical Center Maribor, 2000 Maribor, Slovenia 2 Department of Endocrinology and Diabetology, Clinic of Internal Medicine, University Medical Center Maribor, 2000 Maribor, Slovenia 3 Department of Clinical Chemistry, Clinic of Internal Medicine, University Medical Center Maribor, 2000 Maribor, Slovenia 4 Department of Nuclear Medicine, Clinic of Internal Medicine, University Medical Center Maribor, 2000 Maribor, Slovenia Correspondence should be addressed to Sebastjan Bevc, sebastjanbevc@ Received 18 April 2012; Revised 28 June 2012; Accepted 12 July 2012 Academic Editor: Bernard Portha Copyright © 2012 Sebastjan Bevc et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In clinical practice the glomerular filtration rate (GFR) is estimated from serum creatinine-based equations like the Cockcroft- Gault formula (CG) and Modification of Diet in Renal Disease formula (MDRD). Recently, serum cystatin C-based equations, the newer creatinine formula (The Chronic Kidney Disease Epidemiology Collaboration formula (CKD-EPI)), and equatio