原创力文档a method of drusen measurement based on the geometry of fundus reflectance方法基于眼底反射的几何点测量.pdfVIP
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a method of drusen measurement based on the geometry of fundus reflectance方法基于眼底反射的几何点测量
BioMedical Engineering OnLine BioMed Central
Research Open Access
A Method of Drusen Measurement Based on the Geometry of
Fundus Reflectance
1 1 1
R Theodore Smith* , Takayuki Nagasaki , Janet R Sparrow ,
1 2 1
Irene Barbazetto , Caroline CW Klaver and Jackie K Chan
Address: 1Department of Ophthalmology, Columbia University, New York, NY, USA and 2IGT Afdeling Oogheelkunde, 3015 GD Rotterdam,
Netherlands
Email: R Theodore Smith* - rts1@; Takayuki Nagasaki - tn4@; Janet R Sparrow - jrs88@;
Irene Barbazetto - ib206@; Caroline CW Klaver - carolineklaver@; Jackie K Chan - jc804@
* Corresponding author
Published: 18 April 2003 Received: 10 February 2003
Accepted: 18 April 2003
BioMedical Engineering OnLine 2003, 2:10
This article is available from: /content/2/1/10
© 2003 Smith et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all
media for any purpose, provided this notice is preserved along with the articles original URL.
Abstract
Background: The hallmarks of age-related macular degeneration, the leading cause of blindness
in the developed world, are the subretinal deposits known as drusen. Drusen identification and
measurement play a key role in clinical studies of this disease. Current manual methods of drusen
measurement are laborious and subje
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