原创力文档a combination of dopamine genes predicts success by professional wall street traders结合多巴胺基因预测成功到专业的华尔街交易员.pdfVIP
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a combination of dopamine genes predicts success by professional wall street traders结合多巴胺基因预测成功到专业的华尔街交易员
A Combination of Dopamine Genes Predicts Success by
Professional Wall Street Traders
1 1 1,2,3
Steve Sapra , Laura E. Beavin , Paul J. Zak *
1 Center for Neuroeconomics Studies, Claremont Graduate University, Claremont, California, United States of America, 2 Department of Economics, Claremont Graduate
University, Claremont, California, United States of America, 3 Department of Neurology, Loma Linda University Medical Center, Loma Linda, California, United States of
America
Abstract
What determines success on Wall Street? This study examined if genes affecting dopamine levels of professional traders
were associated with their career tenure. Sixty professional Wall Street traders were genotyped and compared to a control
group who did not trade stocks. We found that distinct alleles of the dopamine receptor 4 promoter (DRD4P) and
catecholamine-O-methyltransferase (COMT) that affect synaptic dopamine were predominant in traders. These alleles are
associated with moderate, rather than very high or very low, levels of synaptic dopamine. The activity of these alleles
correlated positively with years spent trading stocks on Wall Street. Differences in personality and trading behavior were
also correlated with allelic variants. This evidence suggests there may be a genetic basis for the traits that make one a
successful trader.
Citation: Sapra S, Beavin LE, Zak PJ (2012) A Combination of Dopamine Genes Predicts Success by Professional Wall Street Traders. PLoS ONE 7(1): e30844.
doi:10.1371/journal.pone.0030844
Editor: Reiner Albert Veitia, Institut Jacques Monod, France
Received July 1, 2011; Accepted December 29, 2011; Published January 24, 2012
Copyright: 2012 Sapra et al. This is an open-access article distributed under
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