原创力文档a review of molecular mechanisms of the anti-leukemic effects of phenolic compounds in honey审查的分子机制anti-leukemic蜂蜜中酚类化合物的影响.pdfVIP
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a review of molecular mechanisms of the anti-leukemic effects of phenolic compounds in honey审查的分子机制anti-leukemic蜂蜜中酚类化合物的影响
Int. J. Mol. Sci. 2012, 13, 15054-15073; doi:10.3390/ijms131115054
OPEN ACCESS
International Journal of
Molecular Sciences
ISSN 1422-0067
/journal/ijms
Review
A Review of Molecular Mechanisms of the Anti-Leukemic
Effects of Phenolic Compounds in Honey
Murtala B. Abubakar 1,*, Wan Zaidah Abdullah 2, Siti Amrah Sulaiman 3 and Ang Boon Suen 1
1 Department of Physiology, School of Medical Sciences, Universiti Sains Malaysia,
16150 Kubang Kerian, Kelantan, Malaysia; E-Mail: bsang@kb.usm.my
2 Department of Haematology, School of Medical Sciences, Universiti Sains Malaysia,
16150 Kubang Kerian, Kelantan, Malaysia; E-Mail: wzaidah@kb.usm.my
3 Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia,
16150 Kubang Kerian, Kelantan, Malaysia; E-Mail: sbsamrah@kb.usm.my
* Author to whom correspondence should be addressed; E-Mail: murtalababubakar@;
Tel.: +60-14-606-1009 or +234-80 Fax: +609-765-3370.
Received: 4 September 2012; in revised form: 10 October 2012 / Accepted: 25 October 2012 /
Published: 15 November 2012
Abstract: Hematologic malignancies constitute about 9% of all new cases of cancers as
reported via the GLOBOCAN series by International Agency for Research on Cancer
(IARC) in 2008. So far, the conventional therapeutic and surgical approaches to cancer
therapy have not been able to curtail the rising incidence of cancers, including
hematologica
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