原创力文档refining the global spatial limits of dengue virus transmission by evidence-based consensus精炼的全球空间限制登革热病毒传播,以证据为基础的共识.pdfVIP
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refining the global spatial limits of dengue virus transmission by evidence-based consensus精炼的全球空间限制登革热病毒传播,以证据为基础的共识
Refining the Global Spatial Limits of Dengue Virus
Transmission by Evidence-Based Consensus
1,2 1 1 1 3
Oliver J. Brady *, Peter W. Gething , Samir Bhatt , Jane P. Messina , John S. Brownstein ,
4 1 1 5,6 1,6
Anne G. Hoen , Catherine L. Moyes , Andrew W. Farlow , Thomas W. Scott , Simon I. Hay *
1 Spatial Ecology and Epidemiology Group, Department of Zoology, University of Oxford, Oxford, United Kingdom, 2 Oxitec Ltd., Abingdon, United Kingdom,
3 Department of Pediatrics, Harvard Medical School and Children’s Hospital Informatics Program, Boston Children’s Hospital, Boston, Massachusetts, United States of
America, 4 Department of Community and Family Medicine, Dartmouth College, Hanover, New Hampshire, United States of America, 5 Department of Entomology,
University of California Davis, Davis, California, United States of America, 6 Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of
America
Abstract
Background: Dengue is a growing problem both in its geographical spread and in its intensity, and yet current global
distribution remains highly uncertain. Challenges in diagnosis and diagnostic methods as well as highly variable national
health systems mean no single data source can reliably estimate the distribution of this disease. As such, there is a lack of
agreement on national dengue status among international health organisations. Here we bring together all available
information on dengue occurrence using a novel approach to produce an evidence con
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