原创力文档rift valley fever virus seroprevalence in human rural populations of gabon裂谷热病毒阳性率下降人类加蓬的农村人口.pdfVIP
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rift valley fever virus seroprevalence in human rural populations of gabon裂谷热病毒阳性率下降人类加蓬的农村人口
Rift Valley Fever Virus Seroprevalence in Human Rural
Populations of Gabon
1,2. ´ ´ 2. 3 2,4 5
Xavier Pourrut *, Dieudonne Nkoghe *, Marc Souris , Christophe Paupy , Janusz Paweska , Cindy
2 2 1,2
Padilla , Ghislain Moussavou , Eric M. Leroy
´ ´
1 Institut de Recherche pour le Developpement, UMR 190, Marseille, France, 2 Centre International de Recherches Medicales, BP 769, Franceville, Gabon, 3 Institut de
´ ¨ ´
Recherche pour le Developpement, UMR 190, Mahidol University, Nakhon Pathom, Thaıland, 4 Institut de Recherche pour le Developpement, UR 16, Montpellier, France,
5 Special Pathogens Unit, National Institute for Communicable Diseases, Johannesburg, South Africa
Abstract
Background: Rift Valley fever (RVF) is a mosquito-borne viral zoonosis caused by a phlebovirus and transmitted by Aedes
mosquitoes. Humans can also be infected through direct contact with blood (aerosols) or tissues (placenta, stillborn) of
infected animals. Although severe clinical cases can be observed, infection with RVF virus (RVFV) in humans is, in most cases,
asymptomatic or causes a febrile illness without serious symptoms. In small ruminants RVFV mainly causes abortion and
neonatal death. The distribution of RVFV has been well documented in many African countries, particularly in the north
(Egypt, Sudan), east
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