rise and demise of bioinformatics promise and progress生物信息学的承诺和进步的崛起和消亡.pdfVIP

Review Rise and Demise of Bioinformatics? Promise and Progress Christos A. Ouzounis1,2* 1 Institute of Agrobiotechnology, Centre for Research Technology Hellas (CERTH), Thessaloniki, Greece, 2 Donnelly Centre for Cellular Biomolecular Research, University of Toronto, Toronto, Ontario, Canada irrelevance, in x = 651 weeks, or just over a dozen years from now. Abstract: The field of bioinformatics and computational Such a trend cries out for an explanation. Why is it that a field that biology has gone through a number of transformations appeared unstoppable in all its glory just a few years ago might during the past 15 years, establishing itself as a key already be exhibiting signs of (media) fatigue? And does this trend component of new biology. This spectacular growth has indicate lack of progress, lack of interest, both, or none of the above? been challenged by a number of disruptive changes in We take this graph as a stepping stone, an opportunity to discuss the science and technology. Despite the apparent fatigue of above questions, bearing in mind that this is a trends analysis and the linguistic use of the term itself, bioinformatics has grown perhaps to a point beyond recognition. We explore not a strictly scientific discourse on the subject. both historical aspects and future trends and argue that as the field expands, key questions remain unanswered One Explanation: Too Much Promise? and acquire new meaning while at the same time