- 1、原创力文档(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。。
- 2、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
- 4、该文档为VIP文档,如果想要下载,成为VIP会员后,下载免费。
- 5、成为VIP后,下载本文档将扣除1次下载权益。下载后,不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后,您将拥有八大权益,权益包括:VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传,每下载1次, 网站将根据用户上传文档的质量评分、类型等,对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
host cell factors as antiviral targets in arenavirus infection在沙粒病毒感染宿主细胞因子作为抗病毒药物目标
Viruses 2012, 4, 1569-1591; doi:10.3390/v4091569
OPEN ACCESS
viruses
ISSN 1999-4915
/journal/viruses
Review
Host Cell Factors as Antiviral Targets in Arenavirus Infection
Florencia N. Linero, Claudia S. Sepúlveda, Federico Giovannoni, Viviana Castilla,
Cybele C. García, Luis A. Scolaro and Elsa B. Damonte *
Laboratorio de Virología, Departamento de Química Biológica, Facultad de Ciencias Exactas y
Naturales, Universidad de Buenos Aires/IQUIBICEN (CONICET), Ciudad Universitaria, Pabellón 2,
Piso 4, Buenos Aires 1428, Argentina; E-Mails: flinero@qb.fcen.uba.ar (F.N.L.);
claudia@qb.fcen.uba.ar (C.S.S.); fedegiova@ (F.G.); viviana@qb.fcen.uba.ar (V.C.);
cygarcia@qb.fcen.uba.ar (C.C.G.); luisco@qb.fcen.uba.ar (L.A.S.)
* Author to whom correspondence should be addressed; E-Mail: edamonte@qb.fcen.uba.ar;
Tel.: +54-11-4576-3334; Fax: +54-11-4576-3342.
Received: 17 August 2012; in revised form: 31 August 2012 / Accepted: 4 September 2012 /
Published: 13 September 2012
Abstract: Among the members of the Arenaviridae family, Lassa virus and Junin virus
generate periodic annual outbreaks of severe human hemorrhagic fever (HF) in endemic
areas of West Africa and Argentina, respectively. Given the human health threat that
arenaviruses represent and the lack of a specific and safe chemotherapy, the search for
effective antiviral compounds is a continuous demanding effort. Since diverse host cell
pathways and enzymes are use
您可能关注的文档
- high molecular weight glucan of the culinary medicinal mushroom agaricus bisporus is an α-glucan that forms complexes with low molecular weight galactan高分子量葡聚糖的烹饪药用蘑菇双孢菇的α-glucan形式与低分子量半乳糖体复合物.pdf
- high potential of escalating hiv transmission in a low prevalence setting in rural tanzania不断升级的艾滋病毒传播的高潜力低流行率设定在农村坦桑尼亚.pdf
- high mobility group box protein 1 in complex with lipopolysaccharide or il-1 promotes an increased inflammatory phenotype in synovial fibroblasts高机动组盒蛋白1在复杂与脂多糖或il - 1促进增加炎性滑膜成纤维细胞表型.pdf
- high precision signal processing algorithm for white light interferometry白光干涉法的高精度信号处理算法.pdf
- high molecular mass proteomics analyses of left ventricle from rats subjected to differential swimming training高分子量的蛋白质组学分析从大鼠左心室进行微分游泳训练.pdf
- high prevalence of hiv infection among homeless and street-involved aboriginal youth in a canadian setting盛行的艾滋病毒感染中无家可归,street-involved原住民青年在加拿大环境.pdf
- high prevalence of overweight among adolescents in ho chi minh city, vietnam超重的青少年在胡志明市,越南.pdf
- high prevalence of autoantibodies to rna helicase a in mexican patients with systemic lupus erythematosus自身抗体的rna解旋酶在墨西哥系统性红斑狼疮患者.pdf
- high mobility group box 1 potentiates the pro-inflammatory effects of interleukin-1β in osteoarthritic synoviocytes高机动组框1强化interleukin-1β的促炎作用在骨关节炎synoviocytes.pdf
- high mobility group box-1 protein in patients with suspected community-acquired infections and sepsis a prospective study高机动组盒1蛋白在疑似社区获得性感染和脓毒症患者的前瞻性研究.pdf
- host-guest chemistry of tolbutamide主-客体化学的甲苯磺丁脲.pdf
- hotspots of homologous recombination in the human genome not all homologous sequences are equal热点的同源重组在人类基因组中并不是所有的同源序列是相等的.pdf
- host-pathogen studies in the post-genomic erahost-pathogen研究后基因时代.pdf
- hot spots and not spots addressing infrastructure and service provision through combined approaches in rural scotland热点,而不是点解决基础设施和服务提供通过结合方法在农村苏格兰.pdf
- host-defense activities of cyclotides宿主防御cyclotides活动.pdf
- house dust mite major allergens der p 1 and der p 5 activate human airway-derived epithelial cells by protease-dependent and protease-independent mechanisms屋尘螨过敏原主要der p 1和der 5激活人类airway-derived上皮细胞protease-dependent和protease-independent机制.pdf
- housekeeping genes tend to show reduced upstream sequence conservation管家基因倾向于显示减少上游序列保护.pdf
- housing, feeding and management of calves and replacement heifers in swedish dairy herds住房、饲养和管理小腿和更换小母牛在瑞典的奶牛.pdf
- households' perception of climate change and human health risks a community perspective家庭的气候变化和人类健康风险的看法一个社区的视角.pdf
- host strain specific sex pheromone variation in spodoptera frugiperda主持人应变特定的性信息素变化spodoptera frugiperda.pdf
文档评论(0)