原创力文档quantitative analysis of the epithelial lining architecture in radicular cysts and odontogenic keratocysts根端囊肿上皮衬里结构的定量分析和牙原性角化.pdfVIP
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quantitative analysis of the epithelial lining architecture in radicular cysts and odontogenic keratocysts根端囊肿上皮衬里结构的定量分析和牙原性角化
Head Face Medicine BioMed Central
Research Open Access
Quantitative analysis of the epithelial lining architecture in radicular
cysts and odontogenic keratocysts
Gabriel Landini*
Address: Oral Pathology Unit. School of Dentistry, The University of Birmingham, St. Chads Queensway, Birmingham B4 6NN, UK
Email: Gabriel Landini* - G.Landini@bham.ac.uk
* Corresponding author
Published: 17 February 2006 Received: 01 November 2005
Accepted: 17 February 2006
Head Face Medicine 2006, 2:4 doi:10.1186/1746-160X-2-4
This article is available from: /content/2/1/4
© 2006 Landini; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: This paper describes a quantitative analysis of the cyst lining architecture in radicular
cysts (of inflammatory aetiology) and odontogenic keratocysts (thought to be developmental or
neoplastic) including its 2 counterparts: solitary and associated with the Basal Cell Naevus
Syndrome (BCNS).
Methods: Epithelial linings from 150 images (from 9 radicular cysts, 13 solitary keratocysts and 8
BCNS keratocysts) were segmented into theoretical cells using a semi-automated partition based
on the intensity of the haematoxylin stain which defined exclusive areas relative to each detected
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