quantitative protein expression profiling reveals extensive post-transcriptional regulation and post-translational modifications in schizont-stage malaria parasites定量蛋白表达分析显示广泛的转录后调控和转录后修饰在schizont-stage疟疾寄生虫.pdfVIP

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quantitative protein expression profiling reveals extensive post-transcriptional regulation and post-translational modifications in schizont-stage malaria parasites定量蛋白表达分析显示广泛的转录后调控和转录后修饰在schizont-stage疟疾寄生虫.pdf

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quantitative protein expression profiling reveals extensive post-transcriptional regulation and post-translational modifications in schizont-stage malaria parasites定量蛋白表达分析显示广泛的转录后调控和转录后修饰在schizont-stage疟疾寄生虫

Volume 9, Issue 12, Article R177et al.Foth2008 Open Access Research Quantitative protein expression profiling reveals extensive post-transcriptional regulation and post-translational modifications in schizont-stage malaria parasites Bernardo J Foth, Neng Zhang, Sachel Mok, Peter R Preiser and Zbynek Bozdech Address: School of Biological Sciences, Nanyang Technological University, Nanyang Drive, 637551 Singapore. Correspondence: Zbynek Bozdech. Email: zbozdech@.sg Published: 17 December 2008 Received: 19 September 2008 Revised: 1 December 2008 Genome Biology 2008, 9:R177 (doi:10.1186/gb-2008-9-12-r177) Accepted: 17 December 2008 The electronic version of this article is the complete one and can be found online at /2008/9/12/R177 © 2008 Foth et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. electrophoresis reveals significant post-transcriptional regulation./pProtein expression profiling in PlasmodiumpA quantitative time-course analysis of protein abundance for Plasmodium falciparum schizonts using two-dimensional differential gel Abstract Background: Malaria is a one of the most important infectious diseases and is caused by parasitic protozoa of the genus Plasmodium. Previously, quantitative characterization of the P. falciparum transcriptome demonstrated that the strictly controlled progression of these parasites through their intra-erythr