quantitative ultrasonic assessment for detecting microscopic cartilage damage in osteoarthritis定量超声评估检测显微镜在骨关节炎软骨损伤.pdfVIP

Available online /content/7/1/R38 Vol 7 No 1 Open Access Research article Quantitative ultrasonic assessment for detecting microscopic cartilage damage in osteoarthritis 1 2 2 1 Koji Hattori , Ken Ikeuchi , Yusuke Morita and Yoshinori Takakura 1Department of Orthopaedic Surgery, Nara Medical University, Kashihara, Nara, Japan 2Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan Corresponding author: Koji Hattori, hattori@naramed-u.ac.jp Received: 4 Aug 2004 Revisions requested: 1 Oct 2004 Revisions received: 9 Oct 2004 Accepted: 16 Oct 2004 Published: 16 Nov 2004 Arthritis Res Ther 2005, 7:R38-R46 (DOI 10.1186/ar1463) /content/7/1/R38 © 2004 Hattori et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/ 2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Osteoarthritis (OA) is one of the most prevalent chronic and echo duration were selected as quantitative indices. Using conditions. The histological cartilage changes in OA include these indices, the articular cartilage was examined to elucidate surface erosion and irregularities, deep fissures, and alterations the relationships of the ultrasonic analysis with biochemical, in the staining of the matrix. The reversibility of these chondral biomechanical and histological analyses