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protein analysis-on-chip systems in foodomics蛋白质在foodomics analysis-on-chip系统
Nutrients 2012, 4, 1475-1489; doi:10.3390/nu4101475
OPEN ACCESS
nutrients
ISSN 2072-6643
/journal/nutrients
Review
Protein Analysis-on-Chip Systems in Foodomics
Filomena Nazzaro 1,*, Pierangelo Orlando 2, Florinda Fratianni 1, Aldo Di Luccia 1,3 and
1
Raffaele Coppola
1 Institute of Food Science, ISA-CNR, Via Roma 64, Avellino 83100, Italy;
E-Mails: fratianni@r.it (F.F.); a.diluccia@unifg.it (A.D.L.); direttore@r.it (R.C.)
2 Institute of Protein Biochemistry, IBP-CNR, Via P. Castellino 121, Napoli 80124, Italy;
E-Mail: p.orlando@r.it
3 Department of Food Science, University of Foggia, Via Napoli 25, Foggia 71100, Italy
* Author to whom correspondence should be addressed; E-Mail: mena@r.it;
Tel.:+39-0825299102; Fax: +39-0825781585.
Received: 22 May 2012; in revised form: 21 July 2012 / Accepted: 30 September 2012 /
Published: 16 October 2012
Abstract: Protein compositional data can address nutritional, packaging, origin/authenticity,
processing history, safety and other quality questions. Such data has been time-consuming
and expensive to generate until recently but “protein analysis on a chip” systems are now
available that can analyze a complex food sample in a few minutes and do not require great
protein analytical expertise. We review some of the main new approaches with examples
of their application and discuss their advantages and disadvantages.
Keywords: lab-on-chip; protein; microisoelectrofocusing; proteomic; food
1. Protein Analysis and Lab-on-Chip Method
Highlights: Faster and f
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