单双球囊后凸成形术对老年性椎体骨折实验探究.docVIP

单双球囊后凸成形术对老年性椎体骨折实验探究 　 作者：郝润松，孙钢，于志军，刘训伟，金鹏，李凡东，谢志勇,易玉海 【摘要】 ［目的］探讨单、双球囊后凸成形术对治疗老年骨质疏松性椎体压缩骨折的差别。［方法］10具老年胸腰段脊柱标本(T12～L2)，骨密度仪测定椎体骨密度，证实为骨质疏松标本。标本随机分配为单球囊组和双球囊组，每组5具。将标本游离成单个椎体，每具标本选择2个椎体共20个椎体，经万能力学试验机轴向加载，制造椎体压缩骨折，压缩程度为25％，随即行单、双球囊后凸成形术，测定椎体在骨折前、后及骨水泥注入后的高度并记录骨水泥注入前、后最大负荷，计算其刚度。［结果］单球囊组原始椎体最大压缩负荷及刚度分别为(1420±80.55)N 和 (1030.27±50.74)N／mm，骨水泥注入后分别为(2937.9±175.15)N和(963±20.66)N／mm,双球囊组原始椎体最大负荷及刚度分别为(1398±85.35)N和(1024.16±57.50)N／mm， 骨水泥注入后分别为(2800.8±157.79)N和(964.52±22.03)N／mm。单球囊组骨水泥注入后椎体高度恢复率为(96.20±0.01)％；双球囊组骨水泥注入后椎体高度恢复率为(95.30±0.02)％。骨水泥注入后椎体最大负荷及对骨折椎体的高度恢复单球囊组与双球囊组间差异无显著性(Plt;0.01)，椎体刚度差异无统计学意义。两组均未见骨水泥溢出。［结论］单、双球囊椎体后凸成形术生物力学测量结果和椎体高度恢复等实验结果无显著性统计学差异且骨水泥的渗漏率极低。 【关键词】 骨质疏松； 椎体压缩性骨折； 球囊； 椎体后凸成形术 Abstract：［Objective］To compare the difference between single and double balloon kyphoplasty to treat osteoporotic vertebral body.［Method］Twenty osteoporotic vertebral bodies were harvested from 10 embalmed cadavers, alternatingly assigned to either the single and double group. All vertebraes were compressed by 25% of their initial height using materials testing machine to create vertebral compression fractures and determine their augmented strength and stiffness before and after injecting the cement. Precompression,postcompression and posttreatment height of vertebrae were measured.［Result］Both treatments resulted in significantly stronger vertebral bodies relative to their initial state (Plt;0.01)and restored vertebral body stiffness to their initial values. The strongth and the stiffness of the single balloon group were restored from (1420±80.55)N and (1030.27±50.74)N/mm to (2937.9±175.15)N and (963±20.66) N/mm, and those of the double balloon group were also restored from (1398±85.35)N and (1024.16+57.50)N/mm to (2800.8±157.79)N and (964.52±22.03)N/mm. The elevation ratio of both group were (96.20±0.01) % and (95.30±0.02)% respectively. Both treatment resulted in significant restoration of vertebral body height. No vertebral body of both group was found extravasati