愈肝颗粒抗肝纤维化及其对Smad4、Smad7的影响实验的研究.pdf

of fibrous degree Was stable．In degeneration 6weeks the area ofStand4the grouppositive was widestwith stron2 in even staining in dollopshape，it some cells slightlyexpressedhepatic andthe valuesofPA wasthe valvuesofPAand highest，P0．01，the OD of inother Smad4，Smad7 hadno groups of therapyefficacyYGKL：①YGKL6weeks in to4 groupcomparison weeks showedthat：the group valuesof andthe AST,ATL，HA，LN scoresofliverinflammation and activityfibrosis lowered degree significantly,PO．01，howerethe of ALBhadnosfa“sfjca】 recovery significance，P0．05．The sectionsshowedthe pathological inflammation and necrosisof cellswere hepatic narrowedand lightened，fibers septas the structuredeformof lobules In hepatic improved． the ofSmad4 immunohistochemistry decreasedand