膜分离技术在药物分离中的应用-中国变压吸附设备商务网.pdfVIP

T ianj in P harmacy 2010 22 2 65 * (, 300052) , , , , , , , : TQ 460. 6 : A : 1006-5687 ( 20 10) 02-0065-05 Application ofm em brane techno logy in separation of pharmaceutica ls W u Fangn ing ( T ianj in Center or D rug Evalua tion, T ianj in 300052) ABSTRACTM embrane separa tion techno logy has been w ide ly u sed in b iopharm aceutica l indu stry recen tly. A dvances in m em- brane techno logy have been accelerated in the course to m eet the challeng es posed in the rapid deve lopm ent o m ode rn b iotechno lo- gy and pharm aceutica l indu stry. T his article rev iew s recent developm ents and trends in m icro iltra tion, u ltra iltration, nano iltra- tion, reverse osm osis and m olecu larly mi prin ted m em brane techno logy, w ith re lation to the ir app lications in the separation and pur-i ication o pharm aceutica ls. KEY WORDS membrane separation technology, separation o pharmaceutica ls, m icro iltration, ultra iltration, nano iltration ( m embrane separation techno logy) , , , , , [ 1, 2] () , , , : ( MF) ( UF) ( N F) [ 3] , ( RO ) , 1 1 ( M P a) ( M F) \0. 1 Lm ~ 0. 1 ( U F) 10~ 100 nm 0. 1~ 1 ; ( NF) 1~ 10 nm 0