q开关激光联合复方木尼孜其颗粒治疗黄褐斑疗效观察.docVIP

精品论文 参考文献 Q开关激光联合复方木尼孜其颗粒治疗黄褐斑疗效观察 谢洪霞 何 梅 陆 洁 苏怡帆 　　（成都市第二人民医院医疗美容科 四川 成都 610031） 　　【摘 要】目的：观察Q开关Nd:YAG1064nm激光联合口服复方木尼孜其颗粒治疗黄褐斑的临床疗效。方法：将黄褐斑患者60例，随机分为治疗组和对照组，其中治疗组30例，对照组30例。治疗组：接受Q开关Nd:YAG1064nm激光联合复方木尼孜其颗粒口服6g tid治疗；对照组：仅接受Q开关Nd:YAG1064nm激光治疗。观察患者面部皮损的消退情况，有效率以基本治愈和显效两项统计。结果：治疗组总有效率为93.33%，对照组总有效率为73.33%，两组疗效比较，差异均有统计学意义（P＜0.05)。结论：Q开关Nd:YAG1064nm激光联合口服复方木尼孜其颗粒治疗黄褐斑优于单用Q开关Nd:YAG1064nm激光治疗组，适合临床运用。 　　【关键词】黄褐斑；复方木尼孜其颗粒；激光；疗效观察 　　【中图分类号】R242 【文献标识码】B 【文章编号】1003-5028（2015）6-0444-02 　　Study on effect of the treatment for Chloasma by Q-switched 1064nm laser and Compound muniziqi granules 　　【Abstract】Objective：To observe and compare the therapeutic effect of the Chloasma treated by Q-switched 1064nm laser and Compound muniziqi granules.Methods：A total 60 Chloasma cases were divided into two groups.Treatment group contains 30 cases and all of them were treatded by Q-switched 1064nm laser and Compound muniziqi granules. Control group contains 30 cases and all of them were treatded by Q-switched 1064nm laser. The valid cases include the completely cured cases and cases who showed good effect.Results：In treatment group, the total effect rate was 93.33%.In control group,the total effect rate was 73.33%. There was statistic difference in the total effect rate between the two groups(p＜0.05).Conclusion：The therapeutic effect of the Chloasma treated by Q-switched 1064nm laser and Compound muniziqi granules is better than the treatment for Chloasma by Q-switched 1064nm laser.The method is appropriate for Clinical application. 　　【Key words】chloasma;Compound muniziqi granules;laser;Observation of curative effect 　　黄褐斑是临床常见的损容性色素增加性皮肤病，表现为面颊部的褐色至棕褐色斑片，亚洲中青年女性多见[1]。多见于育龄???妇女，男女比例约为1:9[2]。黄褐斑俗称“蝴蝶斑”，“肝斑”，在中医属于“黧黑斑”、“面尘”的范畴。临床治疗方法多种多样，疗效不甚满意，因这种顽固性皮肤病的病因病理的复杂性，至今仍是世界医学治疗的一大难题，笔者科室应用Q开关Nd:YAG1064nm激光联合口服复方木尼孜其颗粒治疗黄褐斑患者，探讨其临床疗效，旨在寻找一种更为安全有效的治疗方法。 　　1 资料和方法 　　1.1一般资料：选取2013年2月～2014年1月门诊就诊的黄褐斑患者中临床分型均为混合型的病例60例，均为女性，年龄22～51岁，平均为38.3岁，病程1～10年，平均3.2年；面积1.0times;1.6cm～4.30t