23G玻璃体切割联合内界膜剥离治疗高度近视性黄斑劈裂的疗效.docVIP

精品论文 参考文献 23G玻璃体切割联合内界膜剥离治疗高度近视性黄斑劈裂的疗效 许立帅 杨小丽(通讯作者) 兰长骏 　　 (川北医学院附属医院眼科 四川南充 637000) 　　【摘要】目的：评估23G玻璃体切割(PPV)联合内界膜剥离(ILMP)及长效气体眼内填充治疗高度近视性黄斑劈裂(HMF)的疗效。方法：收集我院行23G PPV联合ILMP及长效气体眼内填充治疗HMF患者28例(36眼)，术后随访6个月，行视力、OCT及mfERG等检查，并进行统计学分析。结果：患者术后视力较术前均有提高，差异具有统计学意义(Plt;0.05)。OCT提示32眼黄斑区解剖结构恢复，4眼好转。mfERG提示术后6个月时，1环P1波潜伏期较术前缩短, P1波振幅密度提高(Plt;0.05)，mfERG的三维地形图的中央峰逐渐恢复，旁中心凹区域不规则低反应区减少或消失。结论：23G PPV联合ILMP及长效气体眼内填充治疗HMF安全有效。 　　【关键词】玻璃体切割 高度近视 黄斑劈裂 内界膜剥离 　　【中图分类号】R77 【文献标识码】A 【文章编号】2095-1752（2014）15-0314-02 　　Efficacy of 23G vitrectomy in treatment of foveoschisis in high myopic eyes 　　Li-shuai Xu, Xiao-li Yang, Chang-jun Lan 　　Department of Ophthalmology，Affiliated Hospital of North Sichuan Medical Collge，Nanchong，Sichuan 637000，P.R.China 　　【Abstract】Objective: To evaluate the efficacy of 23G pars plana vitrectomy(PPV) with internal limiting membrane peeling(ILMP) associated with gas tamponade in eyes with high myopic foveoschisis. METHODS: 36 eyes of 28 highly myopic patients with foveoschisis who underwent PPV combind with ILMP associated with gas tamponade in our hospital were collected. Visual acuity，mfERG，and OCT were examined prcoperatively and postoperatively.The results were analyzed statistically and compared．RESULTS: For follow-up times of six months, BCVA of all patients improved after treatment. There were statistically significant differences between before treatment and after treatment in BCVA(Plt;0.05). OCT: The foveoschisis completely resolved in 32 eyes and partially resolved in the remaining 4 eyes. mfERG: 6 months postoperatively ,incubation period of wave Pl of ring 1 was shorter than preoperatively , the response densities of wave P1 of ring 1 got higher postoperatively(Plt;0.05), the central peaks of mfERG topographies reappeared little by little during 6 months after the surgery,also the irregular low reaction regions in the parafoveal area were decreased gradually or disappeared. CONCLUS