前列地尔改善慢性肾衰竭患者肾功能的作用.docVIP

精品论文 参考文献 前列地尔改善慢性肾衰竭患者肾功能的作用 昆明同仁医院内二科 云南 昆明 650228 作者简介：王尔萍，女，（1968.07-）本科，副主任医师， 肾内科诊治学。 [摘要]目的：探讨前列地尔在改善慢性肾衰患者肾功能中的临床应用效果。方法：选择2014年1月至2016年1月来我院进行治疗的慢性肾衰患者60例为研究对象，采用随机数字表法，将所有患者随机分为对照组（给予常规治疗）与观察组（常规治疗基础上给予前列地尔治疗），比较两组患者治疗前后Scr（血肌酐）、BCN（尿素氮）、CCr（内生肌酐清除率）和TP/24h（24h尿蛋白定量）水平及不良反应的发生情况。结果：治疗前，两组患者的Scr、BCN、CCr及TP/24h水平无明显差异（Pgt;0.05），治疗后，各项指标明显改善，且观察组改善情况优于对照组（Plt;0.05），两组患者不良反应的发生情况无统计学意义（Pgt;0.05）。结论：前列地尔在改善慢性肾衰竭患者肾功能方面具有十分显著的作用，且不良反应较少，安全性较高，值得在临床进行广泛应用。 关键词:前列地尔；慢性肾衰竭；尿素氮；血肌酐 【中图分类号】R687.4【文献标识码】A【文章编号】1001-5213(2016)09-0355-02 Leading to improve the renal function in patients with chronic renal failure Wang Erping Tongren hospital in kunming in two families, 650228 [abstract] objective: to study the forefront, in improving the clinical application effect of renal function in patients with chronic renal failure. Methods: between January 2014 and January 2016 in our hospital for treatment of 60 patients with chronic renal failure as the research object, using the random number table method, all of the patients were randomly divided into control group (routine treatment) and observation group (conventional treatment on the basis of given fore ground treatment), compared two groups of patients before and after treatment of Scr (serum creatinine), BCN (urea nitrogen) and CCr (endogenous creatinine clearance) and TP / 24 h (24 h urine protein quantitative) level and the occurrence of adverse reactions. Results: before treatment, two groups of patients of Scr, BCN, CCr and TP / 24 h level has no obvious difference (P gt; 0.05), after treatment, the indicators improved significantly, and the observation group to improve the situation is better than that of control group (P lt; 0.05), the occurrence of adverse reactions in patients with two groups has no statistical significance (P gt; 0.05). Conclusion: the front row, in the aspect of improve renal function in patients with chronic renal failure plays a very significant role, and with less adverse reaction, high