原发性颅内软骨肉瘤2例报告及文献复习.docVIP

原发性颅内软骨肉瘤2例报告及文献复习 金凯 赵刚 王育波 张帅 王东东 吉林大学第一医院神经肿瘤外科 X 关注成功！ 加关注后您将方便地在 我的关注中得到本文献的被引频次变化的通知！ 新浪微博 腾讯微博 人人网 开心网 豆瓣网 网易微博 摘????要： 目的:分析2例原发性颅内软骨肉瘤患者的临床资料, 提高对该病的认识和管理。方法:患者1因左眼动眼神经瘫入院, 术前考虑为颅咽管瘤, 术后给予放疗。患者2因视力下降入院, 术前考虑为脊索瘤, 行肿瘤大部分切除。结果:2例患者术后病理均证实为软骨肉瘤。患者1术后症状缓解, 随访至今未见明显进展;患者2术后第10天因发生严重颅内感染而死亡。结论:原发性颅内软骨肉瘤术前极易误诊, 需通过术后病理确诊, 手术是首选治疗方案, 术后辅以放疗可以取得较好疗效。 关键词： 原发性颅内软骨肉瘤; 颅咽管瘤; 脊索瘤; 病例报告; 作者简介：金凯 (1991-) , 男, 浙江省湖州市人, 在读医学硕士, 主要从事神经肿瘤方面的研究。 作者简介：赵刚, 教授, 博士研究生导师 (Tel:0431 E-mail:2956896370@) 收稿日期：2017-03-22 基金：吉林省财政厅科研基金资助课题 (2016swszx031) Primary intracranial chondrosarcoma:A report of 2 cases and literature review JIN Kai ZHAO Gang WANG Yubo ZHANG Shuai WANG Dongdong Department of Neural Tumor Surgery, First Hospital, Jilin University; Abstract： Objective:To analyze the clinical data of 2 patients with primary intracranial chondrosarcoma, and to improve its climical awareness and management.Methods:One patient admitted to the hospital because of his left eye with oculomotor palsy, and he was considered as craniopharyngioma before operation and received radiotherapy after operation.The other patient admitted to the hospital for the vision loss, and he was considered as chordoma and received subtotal resection.Results:Both two patients were confirmed as chondrosarcoma by postoperative pathological examination.One patients clinical symptoms relieved after operation, and there was no obvious progress from the begining of follow-up to now;the other patient died of severe intracranial infection on the 10 th day after operation.Conclusion:Primary intracranial chondrosarcoma is easy to be misdiagnosed before operation and needs to be confirmed by postoperative pathology.Operation is the first choice for its treatment, and the postoperative radiotherapy can achieve the good results. Keyword： primary intracranial chondrosarcoma; cranipharyngioma; chordoma; case report; Received： 2017-03-22 软骨肉瘤是一种起源于软骨细胞的恶性肿瘤, 常发生于青少年, 好发部位为四肢长管骨, 以股骨、胫骨和肱骨多见。原发于颅内的软骨