戊酸雌二醇单独或联合安宫黄体酮降低稽留流产术后并发症疗效观察.docVIP

戊酸雌二醇单独或联合安宫黄体酮降低稽留流产术后并发症疗效观察 何明梅，郭梦 （1.安徽省妇幼保健院急诊科，合肥， 230000 ；2.安徽省妇幼保健院东区，合肥，230000） [摘要]目的：探讨戊酸雌二醇、安宫黄体酮降低稽留流产术后并发症的疗效。方法：选取2010年2月-2014年4月安徽省妇幼保健院收治的，经诊断为稽留流产的150例患者资料，分为人工流产组（A组，46例）及（B组，104例），其中药物流产组再按照随机数字表法分成B1组（50例）和B2组（54例）。A组术后口服戊酸雌二醇1mg 1次/日以及安宫黄体酮10mg/d，B1组术后口服戊酸雌二醇2mg 1次/日，B2组术后不另加服其他药物。术后随访6个月。结果：A组与B1组在治疗稽留流产术后并发症的效果均明显优于B2组，而且A组也略微优于B1组的治疗效果。A组与B1组可以明显降低阴道流血时间、阴道流血量(P0.05)，差异有统计学意义；而且A组与B1组可以明显缩短月经复潮时间、维持经量(P0.05)，差异有统计学意义；A组与B1组术后21天子宫内膜厚度明显低高于B2组(P0.05)，差异有统计学意义；A组与B1组术后宫腔感染明显低于B2组(P0.05)，差异有统计学意义；A组与B1组术后不良反应明显低于B2组(P0.05)，差异有统计学意义；结论：稽留流产术后使用戊酸雌二醇联合安宫黄体酮能够明显降低并发症的发生，具有很好的临床疗效。 【关键词】戊酸雌二醇；安宫黄体酮；稽留流产术 Estradiol valerate, medroxyprogesterone acetate to reduce complications of missed abortion postoperative curative effect observation HE Ming-mei1，GUO Meng2 （1.ANHUI WOMEN AND CHILD HEALTH CARE HOSPITAL, Hefei，230000；2. ） [Abstract] Objective: To study the effects of estradiol valerate, medroxyprogesterone, reduce the postoperative complications of missed abortion. Method: Select the February 2010 -2014 April Anhui MCH hospital, was diagnosed in 150 cases of missed abortion patient data into abortion group (A, 46 cases) and (group B, 104 patients) , which medical abortion group was divided according to the random number table B1 group (50 cases) and B2 group (54 cases). A postoperative oral estradiol valerate 1mg/day and medroxyprogesterone acetate 10mg/d, group B after oral administration of estradiol valerate 2mg/day. Patients were followed-up period of 6 months. Results: Group A and Group B1 results missed abortion complications after treatment were significantly better than in group B2, but also slightly better than Group A and Group B1 treatment. group A，B1can significantly reduce vaginal bleeding, vaginal bleeding (P 0.05), the difference was statistically significant; and group A and group B1 can significantly shorten the time of menstruation , menstrual flow (P 0.05), the difference there was statistically significant ; A group B1 group af