妊娠期高血压疾病血凝指标的变化研究.docVIP

精品论文 参考文献 妊娠期高血压疾病血凝指标的变化研究 赵文艳 （綦江区妇幼保健院 401420） 【摘要】 目的：探讨妊娠期高血压疾病患者血凝指标变化情况。方法：妊娠期高血压疾病患者114例为观察组，根据子痫程度分两组，轻度子痫前期患者41例为A组，重度子痫前期患者73例为B组；正常妊娠孕妇111例为对照组，均行血凝指标检测。结果：观察组凝血酶时间、凝血酶原时间、活化部分凝血活酶时间、纤维蛋白原小于对照组，B组凝血酶时间、凝血酶原时间、活化部分凝血活酶时间、纤维蛋白原小于A组，（P＜0.05）。结论：妊娠期高血压疾病患者伴有不同程度的凝血功能障碍。子痫程度越严重，凝血功能障碍越明显。 【关键词】妊娠期高血压；血凝指标；子痫前期 【中图分类号】R714.25 【文献标识码】A 【文章编号】2095-1752（2015）31-0053-02 【Abstract】Objective To investigate changesof blood coagulation index in patients with pregnancy induced hypertension. Methods 114 patients with pregnancy induced hypertension as observation group. According to degree of preeclampsia, patients were divided into two groups. 41 patients were mild preeclampsia as A group.73 patients were severe preeclampsia as B group. 111normal pregnant women as control group. All staff treated blood coagulation index detection. Results Thrombin time;prothrombin time;activated partial thromboplastin time; fibrinogen in observation group were less than control group. Thrombin time;prothrombin time;activated partial thromboplastin time; fibrinogen in B group were less than A group (Plt;0.05). Conclusion Patients with pregnancy induced hypertension have coagulation dysfunction in different degree. Degree of preeclampsia is more serious, while coagulation dysfunction is more obvious. 【Key words】 Pregnancy induced hypertension; Blood coagulation index; Preeclampsia 妊娠期高血压是临床产科的常见病症，患者体内伴有不同程度的凝血相关指标的异常表达［1］。此次研究选取妊娠期高血压疾病患者114例与正常妊娠孕妇111例行血凝指标检测，现报告如下。 1.资料与方法 1.1 资料 本院2011年2月-2013年10月妊娠期高血压疾病患者114例为观察组，年龄28.1plusmn;5.3岁，孕周34.2plusmn;1.7周，舒张压160.2plusmn;12.7mmHg，收缩压105.6plusmn;11.2mmHg。根据子痫程度分为两组，轻度子痫前期患者41例为A组，年龄27.9plusmn;6.1岁，孕周34.1plusmn;1.8周，舒张压159.7plusmn;10.mmHg，收缩压104.9plusmn;10.5 mmHg；重度子痫前期患者73例为B组，年龄28.5plusmn;5.9岁，孕周34.3plusmn;1.9周，舒张压161.3plusmn;11.4mmHg，收缩压105.8plusmn;11.7 mmHg。正常妊娠孕妇111例为对照组，年龄28.3plusmn;4.7岁，孕周34.0plusmn;1.6周，舒张压118.2plusmn;10.3mmHg，收