山东地区1368例高血压患者糖代谢状况筛查分析.docVIP

精品论文 参考文献 山东地区1368例高血压患者糖代谢状况筛查分析 王云霞 陈丽（通讯作者） （山东大学第二医院 山东济南 250033） 【摘要】 目的:调查原发性高血压患者伴有糖代谢异常的流行病学情况，为早期干预、预防心脑血管并发症提供依据。方法：采用分层整群随机抽样的方法，从糖尿病和代谢综合征患病率山东调查人群中筛选出1368例高血压患者，对其进行糖代谢状况的问卷调查和现场OGTT测定。结果：1368例原发性高血压患者中已知自患糖尿病为347例。剩余的1021例高血压患者行口服葡萄糖耐量试验(OGTT)，其中325人(31.83%)达到了糖尿病诊断标准。总的糖代谢异常者为972例（71.05%）。糖代谢异常组和正常组相比，年龄、腰围、性别、HDL-c、SBP、TC对其有显著的影响，是高血压合并糖代谢异常的独立危险因素。结论: 原发性高血压患者合并糖代谢异常的比例非常高，而日常诊断率却很低。因此对于高血压患者，应高度关注糖代谢情况，并积极进行OGTT，以早期发现和治疗糖代谢紊乱，从而能更多地降低心血管疾病的发生率，提高群众的健康质量。 【关键词】 原发性高血压 OGTT 代谢综合征 【中图分类号】R195 【文献标识码】A 【文章编号】2095-1752（2013）15-0356-03 Screening And Analyzing Of Glucose Metabolism In 1368 Patients With Essential Hypertention In Shan Dong Province Wang yunxia,Chen li(Endocrine department Shan dong university Qi lu hospiatal ,Ji nan City 250012 ) 【ABSTRACT】 Objective:to obtainthe epidemiological situation of gluco-metabolic profile in patients with essential hypertension in Shan Dong province.Methods：Stratified random sampling method was used. 1,368 cases with hypertension Screened from the investigation of diabetes and metabolic syndrome prevalence rate in Shandong Province answered the questionnaire about Metabolic syndrome and received in-site oral glucose tolerance test(OGTT) . Results: 347 patients in 1368 cases with having known diabetes, among the remaining 1021 patients of hypertension，The prevalence rates of newly diagnosed DM and the total impaired glucose regulation(IGR) were 31.83% and 71.05% respectively.Patients with abnormal glucose metabolism have higher age, waist circumference, systolic blood pressure levels, TC and lower HDL-c.Conclusion: Newly diagnosed disturbed glucometabolic status is common among patients with essential hypertension，which had very low diagnose rate in routine work.We must pay more attention to the glucometabolic status of patients with hypertension.Doctors should more actively carry out OGTT to early detect and treat the disorders of glucose metabolism, w