颅内动脉瘤与动眼神经麻痹的相关性分析.docVIP

颅内动脉瘤与动眼神经麻痹的相关性分析 郭平平 吴娜 程洁 万亮 王晓蓉 刘振国 上海交通大学医学院附属新华医院神经内科 上海交通大学医学院附属新华医院神经外科 X 关注成功！ 加关注后您将方便地在 我的关注中得到本文献的被引频次变化的通知！ 新浪微博 腾讯微博 人人网 开心网 豆瓣网 网易微博 摘????要： 目的 比较伴发动眼神经麻痹 (OMNP) 与非动眼神经麻痹 (NOMNP) 的颅内动脉 (IA) 瘤患者在各临床因素之间的差异性, 并为其诊断及治疗提供依据。方法 收集本院神经内科及神经外科2014年1月至2016年12月连续入组的224例经DSA确诊的单侧单发IA患者的临床资料, 记录以下因素:性别、年龄、首发症状、受累眼肌表现、动脉瘤部位及最大直径、是否伴发蛛网膜下隙出血 (SAH) 、手术方式及预后等。对IA的部位进行统计, 并将其中的后交通动脉瘤按照其首发症状分为动眼神经麻痹 (OMNP) 组及非动眼神经麻痹 (NOMNP) 组, 分析两组之间的差异性。结果 (1) 对动脉瘤部位分析统计可知, 后交通动脉 (74例, 33.0%) 最常见; (2) NOMNP组患者发生SAH的概率 (84.91%) 要明显高于OMNP组 (19.05%) 。结论 以动眼神经麻痹为首发症状的患者, 需排除动脉瘤的存在。对于继发于后交通动脉瘤的动眼神经麻痹患者, 给予及时的干预措施, 可预防动脉瘤破裂并改善预后。 关键词： 颅内动脉瘤; 动眼神经麻痹; 后交通动脉; 蛛网膜下腔出血; 相关性; 作者简介：王晓蓉, Email:wangxiaorong@ 收稿日期：2017-05-22 基金：慢性病综合防治项目 (SHD Analysis of correlation between intracranial aneurysms and oculomotor nerve paralysis GUO Ping-ping WU Na CHENG Jie WAN Liang WANG Xiao-rong LIU Zhen-guo Department of Neurology, the Xinhua Hospital, Shanghai Jiaotong University; Abstract： Objective To analyze and compare the differences of clinical factors between patients with oculomotor nerve palsy and without oculomotor nerve palsy, and to provide evidence for the diagnosis and treatment of intracranial aneurysms (IA) .Methods Collect the clinical data of two hundred and twenty four patients withunilateral single IA diagnosed by DSA in the Affiliated Xinhua Hospital of Shanghai Jiaotong University School of Medicine Department of Neurology and Department of Neurosurgery from January 2014 to December 2016, and the following factors were recorded:Sex, age, onset symptoms, involvement of ocular muscle performance, aneurysm site and the largest diameter, whether associated with subarachnoid hemorrhage (SAH) , surgical methods and prognosis.The location of intracranial aneurysms was statistically analyzed and the patients with posterior communicating aneurysms were divided into two groups according to their first symptom:Oculomotor nerve palsy (OMNP) group and Non-oculomotor nerve pals