无创呼吸机联合泵入兴奋剂治疗Ⅱ型呼衰的临床观察.docVIP

精品论文 参考文献 无创呼吸机联合泵入兴奋剂治疗Ⅱ型呼衰的临床观察 陈凤玲 胡晓琼（通讯作者）（都江堰市人民医院 四川都江堰 611830） 【中图分类号】R563.9 【文献标识码】A 【文章编号】1672-5085（2010）28-0141-02 【摘要】目的探讨BiPAP呼吸机通气联合泵入呼吸兴奋剂治疗慢性阻塞性肺疾病（COPD）急性发作合并Ⅱ型呼吸衰竭的疗效。方法 将60例由COPD急性加重引起的Ⅱ型呼吸衰竭患者随机分成两组，实验组给予BiPAP呼吸机通气联用呼吸兴奋剂治疗。对照组采用静脉小剂量持续泵入呼吸兴奋剂治疗，比较治疗前后两组心率变化、生理指标及转归。结果 实验组治疗PaO2与发绀改善情况与对照组有差异，CO2的潴留与心率两组比较无显著性差异。结论 BiPAP呼吸机通气联合静脉泵入呼吸兴奋剂治疗慢阻肺急性发作合并Ⅱ型呼吸衰竭，能显著改善低氧血症，减少气管插管机会。对伴有意识障碍的患者，加用呼吸兴奋剂有一定的协同作用。 【关键词】无创呼吸机 联合静脉泵入 兴奋剂 治疗Ⅱ型呼衰 Non-invasive ventilation combined pump-doping treatment of type Ⅱ clinical observation of respiratory failure Chen Feng Ling，Hu Xiao Qiong(The People Hospital of Dujiangyan611830,Sichuan) 【Abstract】Objective To investigate the BiPAP ventilator pump combined treatment of chronic respiratory stimulant obstructive pulmonary disease (COPD) with acute attack with type Ⅱ respiratory failure. Methods 60 patients with acute exacerbation of COPD caused by the type Ⅱ respiratory failure were randomly divided into two groups, experimental group received BiPAP ventilator treatment combined with respiratory stimulants. The control group, intravenous continuous infusion of low dose stimulant treatment of respiratory, heart rate changes before and after treatment both groups, physiological indicators and outcome. Results The treatment of PaO2 and cyanosis improve the situation and differences between the control group, CO2 in trapping and heart rate showed no significant difference. Conclusion BiPAP ventilator combined with intravenous infusion of acute respiratory stimulant treatment of COPD with type Ⅱ respiratory failure, can significantly improve hypoxemia and reduce opportunities for endotracheal intubation. Of the patients associated with disturbance of consciousness, respiratory stimulants plus a certain synergy. 【Key words】 non-invasive ventilation combined with intravenous infusion of stimulant treatment of type Ⅱ respiratory failure 慢性阻塞性肺疾病（ COPD）是一种完全可逆的气流受限 应用 SPSS13.0统计软件数据以表示，组间均数比较采用为特征的疾病，常并发呼吸衰竭，也是引起肺性脑病及