结肠、直肠癌活检的病理诊断研究.docVIP

精品论文 参考文献 结肠、直肠癌活检的病理诊断研究 何磊 　　（乐山市市中区人民医院病理科 四川 乐山 614000） 　　【摘要】 目的:对结肠、直肠癌活检的病理诊断进行研究。方法：选取2013年3月～2015年3月在我院接受临床诊疗的300例结肠、直肠癌患者以及30例腺瘤癌变患者作为研究对象，诊断时采用活检石蜡切片进行病理诊断，并与术后切除标本病理诊断进行比较。结果：术前经活检可知，300例均诊断为癌的患者，术后经复查切片，184例无法确认癌侵及黏膜下层。随后行手术切除标本均确诊为浸润癌，癌的浸润深度：21例为癌侵及黏膜下层，128例为癌侵及肌层，151例为癌侵及浆膜。经活检诊断为腺瘤癌变的30例患者中，术后标本病理诊断结果：2例局限在黏膜内，4例侵及黏膜下层，9例侵及肌层，15例侵及浆膜。结论：虽然结肠、直肠癌活检具有一定的确诊率，但对无法确诊的病例，不得将其诊断为黏膜内肿瘤，其原因为，经术后切片病理诊断，均可见癌浸润；而且，针对腺瘤癌变可采取黏膜内肿瘤诊断。 　　【关键词】 结肠癌；直肠癌；活检；病理诊断 　　【中图分类号】R574.62 【文献标识码】A 【文章编号】2095-1752（2016）21-0040-02 　　The Research in Pathological Diagnosis of Colorectal Cancer He Lei. Department of pathology,The Peoples Hospital of Shizhong District, Leshan City, Sichuan Province, Leshan 614000,China 　　【Abstract】Objective To study the pathological diagnosis of Colorectal Cancer. Methods 300 patients with colorectal cancer and 30 patients with colorectal adenoma canceration who received clinical diagnosis and treatment in our hospital from March 2013 to March 2015 are selected as the research objects; the pathological diagnosis of paraffin biopsy adopted when diagnose is also used to compare with that of postoperative excision specimen. Results Preoperative biopsy showed that 300 cases were diagnosed as cancer patients. Postoperative biopsy found that 184 cases unable to verify submucosal invasion. Subsequently, we also found that the depth of the tumor invasion: 21 cases of cancer invading submucosal, 128 cases of cancer invading the muscle layer, 151 cases of cancer invading serous membrane. Moreover, postoperative biopsy of 30 cases of colorectal adenoma canceration found that 2 cases were confined the mucosa, 4 cases were invades into submucosa, 9 cases were invaded muscular layer and 15 cases were invaded serous membrane. Conclusion Although there is a certain diagnosis rate of biopsy on colorectal cancer, cases not confirmed cannot be diagnosed with intramucosal tumor. The reason for that is according to the postopera