糖尿病外周血管病变不同部位及相关因素分析.doc

糖尿病外周血管病变不同部位及相关因素分析 摘要 目的： 探讨糖尿病外周血管病变的危险因素及不同部位危险因素有否区别。 方法：对84例2型糖尿病病人的颈动脉及下肢动脉进行彩色动脉超声检查，收集包括年龄、性别、吸烟、血压、胆固醇、甘油三脂、高密度脂蛋白、低密度脂蛋白、HbA1C 、ALB/Cr、C肽、CRP等相关危险因素资料，分析各因素与糖尿病外周血管病变的相关性，比较各因素与颈动脉、下肢动脉血管病变的关系，与外周血管病变的关系。 结果：糖尿病外周血管病变与年龄、C肽和ALB/Cr有显著相关性；颈动脉与下肢动脉病变与血压有统计学差异。 【Abstract】 Objective To investigate the risk factors of peripheral vascular disease in diabetic patients and weather there are diffrents with the risk factors in different parts. Methods The arteries of bilateral lower extremities and carotid in 84diabetic patients?examined using colour Doppler，coiiecting the risk factors include age，sex，smoking，blood pressure ，chocesterin，TG，HDL-C，LDL-C，.HbA1c，ALB/Cr，Ctai，CRP，Conclusion to study the relationship between the risk factors and the peripheral vascular disease in diabetic patients，compare diaˉbetes reationship diagnostic value of colour Doppler in lower extremity arterial disease（LEAD）in diabetic patients and its risk factors.Methods The arteries of bilateral lower extremities in60diabetic patients?and40normal controls were examined using colour Doppler to study the relationship between LEAD and diaˉbetes.The patients were divided into2groups according to blood glucose level to study the risk factors of LEAD.Reˉsults The examination indicated that lower extremity atherosclerosis were found in90percent of the diabetes group.This figure is significantly higher than that of the control group，which records72.5%（P0.05）.Moreover，lower extremity atherosclerosis were formed mostly belowknee joints and the occurrence rate of artery narrowing and blocking were found higher in the diabetic group than the control group（P0.01）.An analysis of risk factors showed that diˉabetic lower extremity arterial disease is irrelevant to diabetic development and TC level，but is positively related?to age，blood sugar level，HbA1c，TG，LDL-C and conversely related to HDL-C.Conclusion Colour Doppler is highly sensitive，and helpful to the early diagnosis of LEAD.The formation an