高血压患者胆红素、血脂水平与冠状动脉病变严重程度的相关性分析.docVIP

精品论文 参考文献 高血压患者胆红素、血脂水平与冠状动脉病变严重程度的相关性分析 单爽 （辽宁省凌源市中心医院循环内科 122500） 　　【摘要】目的:分析探讨高血压患者冠状动脉病变的严重程度与胆红素、血脂水平之间的相互关系。方法:选取434例高血压病患者，将冠状动脉主要血管或分支狭窄狭窄lt;50% 患者204例作为对照组，gt;50%的230例患者作为观察组。比较两组胆红素、血脂等生化指标差异。结果:发现观察组高密度脂蛋白胆固醇(HDL-C) 及血胆红素水平较对照组明显降低，三酰甘油( TG) 及低密度脂蛋白胆固醇( LDL-C) 水平明显高于对照组，差异均具有统计学意义( Plt;0.05) 。 结论:胆红素水平在生理范围内增高是延缓高血压病发展为冠心病的保护因素；血脂水平与高血压病患者向冠心病进展相关。 　　【关键词】高血压病 胆红素 血脂 冠心病 相关性 　　【中图分类号】R541 【文献标识码】A 【文章编号】1672-5085（2013）51-0026-02 　　Bilirubin patients with high blood pressure and blood lipid levels and coronary artery lesion severity of correlation analysis 　　【Abstract】 objective: to analyze the severity of coronary artery lesions in hypertension patients and the relationship between bilirubin, blood lipid level. Methods: selected 434 patients with essential hypertension, coronary artery branch main blood vessels or narrow lt; 50% of patients 204 cases as control group, gt; 50% of 230 cases of patients as observation group. Compare two groups of bilirubin, blood lipid and biochemical indexes such as difference. Results: found observation group of high-density lipoprotein cholesterol (HDL - C) and the blood bilirubin level significantly lower than the control group, three acyl glycerin (TG) and low-density lipoprotein cholesterol (LDL - C) level is significantly higher than that of control group, the differences were statistically significant (P lt; 0.05). Conclusion: increased bilirubin level in the physiological range is delay the protection of hypertension for the development of coronary heart disease; Lipid levels were associated with high blood pressure patients to the progress of coronary heart disease. 　　【Keywords】 hypertension; Bilirubin; Blood lipid; Coronary heart disease (CHD),correlation 　　血清胆红素及血脂与冠心病的关系越来越受到重视临床重视，为了了解这些因素在单纯高血压病患者及高血压合并冠心病患者之间存在的不同，初步探讨胆红素与冠状动脉病变程度的相关性及可能机制，以期能早期采取干预措施改善高血压患者的预后，我们收集了我院434例高血压患者的信息来进行分析对比。 　　1 资料与方法 　　1.1临床资料 选取2009年3月 至2013 年3月在我院行冠状动脉造影的高血压