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腹泻儿童肠道蛋白质丢失的临床分析word格式论文
优秀毕业论文
精品参考文献资料
Clinical Analysis for Intestinal Protein Loss in Children with Acute Infective Diarrhea
MD Candidate WANG Hong-Li Supervisor GONG Si-Tang
Abstract
Objective
To investigate the status of intestinal protein loss in children with acute infective diarrhea.
Subjects and Methods
Subjects
Acute diarrhea group : 125 patients with acute diarrhea were researched from the Department of Gastroenterology of Guangzhou Women and Children’s Medical Center between Feb.2009 and Oct.2010.All their data should be integrated.
Control group. 49 children hospitalized with gastrointestinal foreign body or esophageal stenosis, after the esophageal balloon enlargements in the Department of Gastroenterology in the same period.
Methods
To collect the general data of the case and control groups, including age, gender, feeding patterns, weight and the diarrhea episode before admission.
To gather the test results for their level of serum total protein (TP), albumin (ALB),
and prealbumin (PA), C-reactive protein (CRP), and the routine and pathogenic examination for the stool systematically.
To collect the veno us blood and the 24- hour stool of case group and control group within 3 days after admission. Repeat 2 or 3 times if necessary, and then take the mean value.
To measure the concentration of the a1-AT in serum and stool by Enzyme- linked
immunosorbnent assay (ELISA).
Using Curve Expert 1.4 to process the ELISA results.
Using SPSS 16.0 to analyze the results between acute diarrhea group and control group. The test results of TP, ALB, PA, CRP, the total volume of stool per day, the
a1-AT level in serum and stool, the a1-AT clearance were expressed in
x ??s
style.
And these indexes between virus group, bacterial group and control group were analysised by One –Way ANOVA, the detection rate for intestinal protein loss between these groups was analysised by Chi-Square test or Fisher exact test; a=0.05,difference was considered statically significantly for P0.05.
To fol
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