可回收循环使用磁性纳米粒子负载钯催化剂制备及其在有机合成中应用-preparation of recyclable magnetic nanoparticle - supported palladium catalyst and its application in organic synthesis.docx

可回收磁性纳米粒子负载钯催化剂的制备及其在有机合成中的应用摘要aldehydes in excellent yields. The catalyst is readily makeable, easily recoverable, and reusable at least 8 times without significant activity loss.3. A recyclable MNPs-triazole-Pd catalyst for the direct C-2 arylation of indoles reactions has been developed. A variety of substituted indoles reacted with different aryl boronic acids in the presence of 2.0 mol% supported palladium catalyst, affording the corresponding products in good yields. It is important to note that the supported catalyst could be recovered and reused at least 6 times with a slight loss of its reactivity. The operationally simple procedure for the catalyst preparation and recovery of the catalyst make it an ideal catalytic system for the direct C-2 arylation of indoles reaction.Key words: Recyclable magnetic nanoparticles, Supported palladium catalysts, Hiyama crosscoupling reaction, Selective oxidation of alcohols, Direct C-2 arylation of indoles.V目录第一章 背景介绍..................................................................................................... 11.1 引言.................................................................................................................... 11.2 可回收循环使用磁性纳米粒子催化剂.............................................................. 21.3 可回收循环使用磁性纳米粒子催化剂在有机合成中的应用 ........................... 21.3.1 碳碳键偶联反应 ............................................................................................. 31.3.2 氢化反应......................................................................................................... 61.3.3 氧化反应......................................................................................................... 71.3.4 不对称合成..................................................................................................... 91.4 总结 .................................................................................................................. 101.5 参考文献...............................................................