培训资料宫腔粘连.pptVIP

* 胚胎干细胞（Embryonic stem cells） 成体干细胞（Adult stem cells） 肿瘤干细胞（Cancer stem cells） 干细 胞 特征 发生学 * 全能干细胞（totipotent SC）：具有自我更新和分化形成任何类型细胞的能力，有形成完整个体的分化潜能（相当于卵裂球细胞）。 多潜能干细胞（pluripotent SC）：有分化成多胚层细胞的能力，但不能分化成完整个体（相当于胚胎干细胞）。 专能干细胞（unipotent SC）：存在于身体各部，只能向单一方向分化，产生一种类型的细胞（相当于组织内的成体干细胞）。 干细 胞 特征 分类 * 全能 多能 专能 成体干细胞的分化 * 成体干细胞的可塑性 * Maruyama T, Reproduction, 2010, 140:11–22. * 子宫内膜干细胞——Side Population Cells Masuda H, Matsuzaki Y, Hiratsu E, Ono M, Nagashima T, Kajitani T, et al. Stem cell-like properties of the endometrial side population: implication in endometrial regeneration. PLoS One 2010;5:e10387. 羊膜移植的病例报道 Conclusion: Amniotic membrane graft after hysteroscopic lysis of severe IUA, might act as a source of stem cells for endometrial regeneration; a role that will be of great value especially in severe IUAs. Further studies to confirm this finding are warranted Received 24 August 2011; accepted 13 December 2011 Available online 4 January 2012 Endometrial reconstruction fromstem cells (Fertil Steril 2012;-:-–-. 2012 by American Society for Reproductive Medicine.) 三维内膜下血流超声学评价 容受性的评价 They are unspecialized cells capable of renewing themselves through cell division, sometimes after long periods of inactivity. Under certain conditions, they can be induced to become tissue- or organ-specific cells with special functions e.g. in bone marrow, stem cells regularly divide to repair and replace worn out or damaged tissues. * Difficult to culture. In vivo rely of a stem cell niche. To control the asymmetric division. Transdifferentiation seen in the lab unproven that is happens in the body. May be a artifact of the lab and like much of stem cell science it largely phemononligical. Proposed model for ectopic and eutopic implantation of menstrual endometrial tissues/cells and subsequent endometrial regeneration and establishment of the endometriotic lesion. 月经复潮并妊娠 患者出院后给予补佳乐4mg/d后10天加用黄体酮周期治疗； 术后5个月恢复月经，量少，4天干净； 2011年5月试孕3个月后妊娠。 成功分娩 2012年1月19日因“宫内孕34+4