英夫利西单抗类克联合甲氨蝶呤治疗as对患者外周血il-17水平 疾病活动度与生存质量的影响-effect of infliximab combined with methotrexate in the treatment of as on disease activity and quality of life of patients with peripheral blood il - 17 level.docxVIP

万方数据 万方数据 目录 中英文缩略词表·····················································3 中文摘要···························································6 英文摘要···························································9 正文部分··························································12 前言······························································12 第一部分：类克联合甲氨蝶呤治疗 AS 对外周血 IL-17 表达水平与疾病活动度若 干指标的影响······················································14 引言······························································14 材料与方法························································16 结果······························································25 第二部分：类克联合甲氨蝶呤治疗 AS 对 IL-23、TNF-α的影响············31 引言······························································31 材料与方法························································33 结果······························································38 第三部分：类克联合甲氨蝶呤治疗 AS 对生存质量（ SF-36 ） 的影 响································································41 引言······························································41 材料与方法························································42 结果······························································45 全文讨论··························································49 全文结论··························································55 参考文献··························································56 致谢······························································60 综述······························································61 参考文献··························································65 攻读硕士研究生期间发表的论文······································67 ２ 英文缩略词表 英文缩写 英文全称 中文 A DCC A ICAR a ntibody-dependent cell-mediated cytotoxicity a minoimidazole c arboxamide ribonucleotide 抗体依赖的细胞 介导的细胞毒性作用 氨基咪唑甲酰胺 核苷酸 A S A SAS B ASDAI B ASFI ankylosing S pondylitis Assessment of Spondyloarthritis Internation S ociety B ath A nkylosing Spondylitis D isease A ctivity Index Bath Ankylosing S pondylitis Function Index