新生儿肺炎患者中血清SIL-2RCRP及心肌酶水平研究.docVIP

新生儿肺炎患者中血清SIL-2RCRP及心肌酶水平研究 　　[摘要] 目的 探讨血清可溶性白介素2受体（SIL-2R）、C反应蛋白（CRP）及心肌酶水平在新生儿肺炎中的检测意义，以为其诊断及治疗提供依据。 方法 选取2009年3月~2011年10月本院的37例新生儿肺炎患者为观察组，检测其血清SIL-2R、CRP及心肌酶水平，并与同期的37名健康新生儿（对照组）进行比较。 结果 观察组的血清SIL-2R、CRP及LDH、CK、CK-MB、AST水平均高于对照组，且急性期、重症及病毒性肺炎患者的水平均较其他患者要高（P ＜ 0.05），而感染性与吸入性肺炎差异无统计学意义（P ＞ 0.05）。 结论 血清SIL-2R、CRP及心肌酶水平与新生儿肺炎有较为明显的相关性，可为其治疗诊断提供依据。 　　[关键词] SIL-2R；CRP；心肌酶；新生儿肺炎；诊断价值 　　[中图分类号] R722.13+5[文献标识码] A[文章编号] 1673-7210（2012）03（c）-0075-03 　　Study on the correction between the serum SIL-2R, CRP, myocardial enzyme and neonatal pneumonia 　　ZHANG GuohuaCHEN ChunxiHE Jianqing 　　Department of Pediatric, the People′s Hospital of Xishui County, Hubei Province, Xishui 438200, China 　　[Abstract] Objective To study the detection ignificance of the serum soluble interleukin 2 receptors (SIL-2R), C-reactive Protein (CRP), myocardial enzyme in neonatal pneumonia, in order to provide evidence for the diagnosis and treatment. Methods 37 patients with neonatal pneumonia in our hospital from March 2009 to October 2011 were selected as observation group, and the serum SIL-2R, CRP and myocardial enzyme of patients were detected. The levels of were compared to those of 37 healthy newborn infants at the same time. Results The serum SIL-2R, CRP and LDH, CK, CK-MB, AST were all higher than those of control group, levels of patients at acute stage, and viral pneumonia were higher than those of other patients (all P ＜ 0.05), there were all significant differences, but the levels of infectious pneumonia and aspiration pneumonia had no significant differences (P ＞ 0.05). Conclusion There are obvious correction between the serum SIL-2R, CRP, myocardial enzyme and neonatal pneumonia, and it can provide evidence for the diagnosis and treatment. 　　[Key words] SIL-2R；CRP；Myocardial enzyme；Neonatal pneumonia；Diagnostic value 　　新生儿肺炎是新生儿时期最常见的一种严重呼吸道疾病，以弥温性肺部???变及不典型的临床表现为其特点，需及早诊断和正确处理[1]。而早期的诊断及治疗对于改善预后起着非常重要的作用，如不能及时诊断治疗则可能引起呼吸衰竭、心力衰竭、败血症乃至死亡[2]。本文中笔者就血清可溶性白介素2受体（SIL-2R）、C反应蛋白（CRP）及