调补肾气治疗不孕症实验研究.docVIP

调补肾气治疗不孕症实验研究 　　【中图分类号】：R271.14 【文献标识码】：A 　　【文章编号】： 1004-597X(2007)12-0051-03 　　【摘要】 根据中医“气一元论”的理论，拟用调补肾气的补肾助孕合方对排卵障碍性不孕症进行了实验研究。结果，实验动物症状明显改善，卵巢湿重明显增加，卵巢可见原始卵泡及大量初级卵泡、次级卵泡和接近成熟的卵泡，黄体较多，间质少，间质腺少见。说明“肾气虚”是导致卵巢功能异常的病理基础，肾虚是不孕的病机本质，应用调补肾气的方法治疗排卵障碍性不孕症有明显疗效，论证了中医“百病皆生于气”的疾病观，完善和丰富了中医“气一元论”理论的内涵。? 　　【关键词】 气一元论；肾气；不孕症? 　　 　　Transfers to a new post the kidney gas to treat the sterility the experimental study? 　　YANG Zai-gang? 　　【Abstract】 according to the Chinese medicine“ was mad monism ”the theory, planned with to transfer to a new post the kidney to be mad invigorates the kidney helps is pregnant gathers Fang Dui to ovulate the barrier sterility to conduct the experimental study. Finally, the experimental animal symptom distinct improvement, the ovaryobvious increase, the ovary obviously primitive graafian follicle and the massive primaries follicle, the secondary follicle and approach the mature graafian follicle, Huang Tijiao many, nature few, the nature gland is rare. Explained “the kidney ” is causes the ovary function unusual pathology foundation, the kidney empty isthe pathogenesis essence, the application to transfer to a new post the method treatment ovulation barrier sterility which the kidney was mad to have the obvious curative effect, has proven the Chinese medicine “all the various illnesses all had been born in the gas” disease view, consummated and enriches the Chinese medicine “to be mad the monism” the theory connotation.? 　　【key word】is mad the monism; Kidney gas; Sterility 　　 　　不孕症（infertility）是大龄妇女的常见病和多发病。资料表明，我国大龄妇女不孕症的发生率约为10%，排卵障碍引起的不孕占不孕症的15 ~ 25%[1]。而在排卵障碍性不孕患者中，属肾虚者占患者总人数的68%[2]。中医学认为，本病发生多因“肾-天癸-冲任-胞宫”生殖轴功能失调、肾气亏虚所致，张氏等认为“肾气虚”是导致卵巢功能异常的病理基础，治疗排卵障碍性不孕症应从肾入手[3]。人体是一个有机的整体，脏腑、气血、经络不可分割。肾气变动必然影响其他脏腑，扰乱气机，最终使“肾 - 天癸 - 冲任 - 胞宫”生殖轴严重失调，正如王永炎所言：“肾虚是不孕的病机本质” [4]。? 　　 　　1 实验动物及研究方法? 　　 　　1.1 实验动物：SD大鼠9日龄♀幼鼠47只，体重8g，由贵阳医学院实验动物中心提供。实验动物质量合格证号0200161，许可证号SCXK（黔）2002-001。分组：将SD大鼠9日龄♀幼鼠自7日龄购回，适应饲养2日后于第9日按俞瑾等实验方法造模，至30日龄随机分成3组：正常对照组（简称C组）16只；