酒精性脂肪肝与非酒精性脂肪肝患者生化指标比较分析.docVIP

酒精性脂肪肝与非酒精性脂肪肝患者生化指标比较分析 　　[摘要] 目的:探讨酒精性脂肪肝和非酒精性脂肪肝的生化指标特点,提高临床诊断率。方法:120例研究对象分为酒精性脂肪肝组和非酒精性脂肪肝组,每组60例,检测两组患者的血清三酰甘油(TG)、胆固醇(CHOL)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白AⅠ(ApoAⅠ)、载脂蛋白B(ApoB)、尿酸(UA)、空腹血糖(FPG)、天门冬氨酸氨基转移酶(AST)、丙氨酸氨基转移酶(ALT)、AST/ALT、清蛋白(ALB)、球蛋白(GLB)、谷氨酰转移酶(GGT)、总胆红素(TB)和直接胆红素(DB)等生化指标,并进行比较分析。结果:酒精性脂肪肝组的血清三酰甘油(TG)、胆固醇(CHOL)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白B(ApoB)和空腹血糖(FPG)的异常率低于非酒精性脂肪肝组,而高密度脂蛋白胆固醇(HDL-C)、天门冬氨酸氨基转移酶(AST)、AST/ALT(≥2)和直接胆红素(DB)的异常率则高于该组。结论:AST、AST/ALT(≥2)、GGT、UA等指标是鉴别酒精性脂肪肝与非酒精性脂肪肝有效的诊断指标。 　　[关键词] 酒精性脂肪肝;非酒精性脂肪肝;肝功能 　　[中图分类号]R446.11+2 [文献标识码] B[文章编号] 1673-7210(2009)08(b)-067-03 　　 　　Alcoholic fatty liver and non-alcoholic fatty liver in patients with a comparative analysis of biochemical indicators 　　YE Zhujun, LIN Wanmei, YE Shuxia ,LI Fu 　　(Department of Laboratory, Dongguan Daojiao Hospital, Dongguan 523176,China) 　　[Abstract] Objective: To investigate the alcoholic fatty liver and non-alcoholic fatty liver in patients with biochemical indicators of the characteristics, enhance the rate of clinical diagnosis. Methods: 120 cases of research subjects were divided into alcoholic fatty liver group and non-alcoholic fatty liver group, 60 cases of each group, testing the two groups of patients with serum triglyceride (TG), cholesterol (CHOL), high density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein AⅠ(ApoAⅠ), apolipoprotein B (ApoB), uric acid (UA), fasting plasma glucose (FPG), aspartate Histidine aminotransferase (AST),alanine aminotransferase (ALT), AST/ALT, albumin (ALB), globulin (GLB), glutamyltransferase (GGT), total bilirubin (TB) and direct bilirubin (DB) and other biochemical indicators, and comparative analysis. Results: The alcoholic fatty liver group serum triglyceride (TG), cholesterol (CHOL), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (ApoB) and fasting plasma glucose (FPG) of the abnormal rate of low in non-alcoholic fatty liver group, and high-density lipoprot