常规抗青光眼药物副反应的临床分析-clinical analysis of side effects of conventional anti-glaucoma drugs.docxVIP
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常规抗青光眼药物副反应的临床分析-clinical analysis of side effects of conventional anti-glaucoma drugs
上海麓二睡科大学硕士警证论文誊蠛撬尝巍激蓊燧副爱簌斡蕊藤磺究上海麓二睡科大学硕士警证论文誊蠛撬尝巍激蓊燧副爱簌斡蕊藤磺究中文摘要醛靛:鼹察辩娥捷毒竞壤藏糖鹣潮菠陂,了瓣骞静袭耪簸豢霓静尉茇巍,糊辩瓣3 种蓊糨(O.5%嚷吗心胶、装开朗、j);{德樾)进行阮较。观察萁蓊戆剿反应大夺,戳 辩导临廉用翡。 方法:蕊舞?7镬苦簿类黧毒光戳怨鬻(继发褴黉巍黢5簌、惫幢翔魏激辩党黻8 嬲、精生囊蛰缝毒光疆4镔、开想燕!蠢毙鼹22磷、骥毪藤惫褒赘巍眼34镧、潜瓣 综台缓3饿、OHT。l蘸),其中女没蕊蠢46镄,簧瞧患者3l裰,邑完成警术瓣 榭,来送孬手謇47巍,每癸27箩蕊8S爹,乎鹭零龄秘箩。分裂菠爝8转不鼹蕊 赣竞蔽瑟臻(0.5%篷爨心羧、1%遴整卡黠、2冁涯簧专蒜、移,2%§露浃投、煲镌蔽、 装开朗、0,005%适利达及滁立l{lj)。投瘸人用魏不同进行分筑与比较,观黎戮反应}{鐾性搴娥褰的麓貔以及每静药物最嚣鼹辫副反应,另外通过卡方黢骏逝铰3葶枣麓谚 (0+5%壤鸦心黢、美牙翘、爨题攫》瀚澍浸盛大,j、。 结果:掰反应阳性率缀商的药物越0%腻謦卡黼,为42.85%,最常见的剿戚穗浅黼 为刺瘸;其次蹙美开朗,副反应率为36。36%,常见的副反戍表现为刺痛;以薅僚次 兔爨毯校,戮惹应拳35.48%,翥露瓣鲻茨瘟袭璐为瓣薅;{%嚣麓卡潞,裂裁缝枣 30。43%,繁强的巍反应表臻为裁臻瓣心簿;0.2%N法羧,嚣度鹰率29,4i%,鬻见瓣 黪;反应焱蕊烫褪妨搂糍、霸于帮醺躐;瓣裁反艨耀缝零最,l、懿蕊黪莲o,5%噻驾心簸 24+39%,露霓篷受爱瘦衰强为躐瘸。3耱翁燧(o。5%噻避心麓、蓑西麓、颤稳械) 溺爱盛鬻鹱搴圪较差霁无要箸髂意义(PO.05),诱褥这3簿蘩黪翁裂菠褒袭夸率 无显著健蓑异。 缭埝:落娥撬毒党缀药狻帮存在糖~窥瀚剩作鼹,爵其中副反废枣黢菇懿秘黝憝2% l蕃磐卡鹣,露凳兹裁及瘟表现为鲻瘸,iriig*_|爱纛攀最小熬药黪楚o.5%噻褥心黻,嚣 觅的副反虑同样表现为蒯痛。O.5%嚷嚼心胺、美开朗和贝他根这3张药物鳓剐眨应 发生率无撼麓性差异,均可作为抗’潆巍峨篱物的一耱主要选择。关键谣;毒毙隈、骜耪治疗、裂鹱盛上海辩二二隈科大学硕士学位论文Clinical上海辩二二隈科大学硕士学位论文Clinical Study of the side effects of routinely prescribedantiglaucomatous drugsAbstractPurpose:To observe the comnlon side effects associated with antiglaucomatous drugs;to analyze the specific side effects associated with each particular medication,and,moreover, tomake箍statisticalcomparisonofthe sideeffects oftbreedrugs国.5%Timolol,Mekatan, Betagan)in particular.in order to offer guidance for clinical USe.Materials and Methods:The辩tal number of patients Was 77,(secondary glaucoma 5,acute angle closure glaucoma 8,neovascular glaucoma 4,open-angle glaucoma 22,chronic angle closure glaucoma 34,glaucomato—cyclitic syndrome 3,ocular hypertension 1)of whom 46 were female,3 t mate.30 patients had previously undergone surgery,47 had not been operated.The patients’ages ranged from 27 to 85,and averaged 56 years.Eight types of drugs were tested:0,5%Timolol。1%Pilocarpine,2%Pilocarpine, 0。2%Brimonidine,Betagan,Xalatan,Mikelan,and Brinzolamide eye drops.Subjects were grouped for comp’ison according tO the type of drug used。The drugs were
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