苯并咪唑衍生物的合成 生物活性及超分子凝胶的分析-synthesis and biological activity of benzimidazole derivatives and analysis of supramolecular gel.docxVIP

ABSTRACTInthispaper,fromthepointofviewofmoleculardesignthreeseriesofcompoundscontainingthebenzimidazolegrouphavebeensynthetized.Bychangingthemolecularstructure(Benzimidazol1,2and3forthefunctionmodification),theirbiologicalactivityandtheabilitytogelhavebeenregulatedsuccessful.Respectively,weobtained2-phenoxymethylbiscarboxyl-functionalizedbenzimidazolederivative,2-pentadecylbiscarboxyl-functionalizedbenzimidazolederivative(multipleresponsesmetal-organicgelsandtheiradsorptionofthedye)andbis-Schiff-Basefunctionalizedlong-chainalkylbenzimidazolederivative(selectiverecognitionofanionsasgelator).Themainconclusionsareasfollows:Section1ThissectionmainlysummarizedtheapplicationofBenzimidazolederivativesandtheresearchprogressofsupramoleculargelsrespectively.Section2Ninenew2-phenoxymethylbiscarboxyl-functionalizedbenzimidazolederivativehavebeensynthesizedandcharacterizedbyIR,NMRspectra.Thesinglecrystalstructuresofthecompound2-phenoxymethyl-1-carboxymethylbenzimidazoleweredeterminedbyX-raydiffraction.Thebiologicalactivityoftheninecompoundshavebeentested,theresultshowedthatthecompoundshaveplantgrowthregulatingactivityandantibacterialactivity.Section3SupramolecularmetallogelscontainingPb(II)havebeensynthesizedthroughtthereactionofD15andPb(NO3)2.FromthestudywefoundthatD15-Pbcomplexationwasproposedastheprimarygel-formingforce.Theresultinggelsdisplayagoodstimuli-responsivetopH,EDTA,Na2SandNH3·H2O.Inaddition,themetallogelsalsoshowsatendencyineffectivemethylorangedyeremovalagent..So,thismetallogelshavethepotentialtobeexploitedforthedevelopmentofnewsmartsoftmaterials.Section4Sixnew2-long-chainalkylbis-Schiff-BasefunctionalizedbenzimidazolederivativehavebeensynthesizedandcharacterizedbyIR,NMRspectra.CompoundI15canformagelinavarietyofsolvents,thestudyfoundthathydrogenbondingisthemaindrivingforcefortheformationofagel,itdisplayagoodresponsivetoF－,?CH3COO－andH2PO4.WealsomeasureditsUVabsorptionspectraandfluorescenceemissionspectra,andthesameresultsshowedthat,I15inDMSOachieveddualchannelident