Volumetric Automatic Breast Density Assessment in an …：容量自动乳腺密度评估一….pptVIP

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2018-06-29 发布于浙江
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Volumetric Automatic Breast Density Assessment in an …：容量自动乳腺密度评估一….ppt

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Volumetric Automatic Breast Density Assessment in an …：容量自动乳腺密度评估一…

Automatic Volumetric Breast Density Assessment in the eXtensible Imaging Platform Rachel Embree and Christina Sillery David Channin, MD, Advisor In Cooperation with Alex Shnayder, Pat Mongkolwat, Ray Wu Overview Introduction Material and Methods Results Discussion Conclusion Introduction What is Breast Density? The breast is composed of fibroglandular tissue embedded in a background of fatty tissue. The amount of fibroglandular tissue and fat varies among women. Breast cancer arises in this fibroglandular tissue. Mammography is projection radiography of the breast. In mammograms, dense fibroglandular tissue attenuates more radiation than does fat. Breast density refers to the appearance of this fibroglandular tissue in a mammogram [5] Breast Density Positively correlated with breast cancer Four to six times greater risk of breast cancer for women with greater than 60% dense tissue [1] Breast density as a risk factor accounts for as many as 30% of breast cancer cases [1] Can be changed by hormonal, dietary and other interventions Assessment of Breast Density in Mammograms Subjective Visual Assessment by Radiologists (Mandatory) Score the breast on a 4-point scale in the Breast Imaging-Reporting and Data System (BIRADS), based on patterns developed by Wolfe [5] Manual Image Processing Techniques (for research) Planimetry Interactive Thresholding Previous Approaches Interactive Thresholding Goal Create a breast density assessment program that is… Automated Volumetric Accurate In the eXtensible Imaging Platform (XIP) Material and Methods What is XIP? eXtensible Imaging Platform Funded by NIH, NCI Cancer Bioinformatics Grid (caBIG) Program A program to share data, informatics tools, technologies and infrastructure between the funded Comprehensive Cancer Centers across the nation Open Source, Open Standards, Open Architecture Platform for development of medical image processing and analysis applications for research and clinical purposes. Will support the DICOM Applicati