180例高血压病中医证型分布与动脉弹性相关性研究.docVIP

180例高血压病中医证型分布与动脉弹性的相关性研究 　　[摘要]目的 探讨大动脉硬化度在高血压病患者不同中医证型间的差异性。 方法 对180例高血压病患者进行研究，分析PWV在不同中医证型间比较及各影响因素对PWV值的影响。 结果 PWV数值的影响因素有心率、年龄、坐位上臂收缩压、坐位上臂舒张压、脉压差及是否合并冠心病，PWV在中医各证型之间差异有统计学意义（P阴虚阳亢证痰湿壅盛证阴阳两虚证。 结论 （1）肝阳上亢型高血压病患者发生血管意外及脑血管意外事件概率更高。（2）坐位上臂收缩压、坐位上臂舒张压、年龄、心率、脉压差是PWV的显著影响因素。 　　[关键词] 中医证型；高血压病；血压；PWV 　　[中图分类号] R259 [文献标识码] A [文章编号] 2095-0616（2014）24-45-03 　　Correlation study of TCM syndrome type distribution and arterial elasticity on 180 cases of patients with hypertensive 　　ZHANG Baozhu LIU Yanhong LI Fangshuai WANG Fei WANG Xiaosu 　　HUANG Lu DAI Guofang 　　Department of Cardiology， Luoyang No.1 Hospital of Traditional Chinese Medicine， Luoyang 471000， China 　　[Abstract] Objective To study the difference of artery hardenability in different TCM syndrome types in patients with hypertensive. Methods The data of 180 patients were studied. Analyzed the difference of PWV between different TCM syndrome types and the influence of variousing factors on the value of PWV. Results The heart rate， age， sitting systolic pressure of upper arm， sitting diastolic pressure of upper arm， pulse pressure and whether merger of coronary heart disease were the influencing factors of PWV value， and there were significant differences between different TCM syndrome types（PYin deficiency and Yang hyperactivityexcessive phlegm-dampnessYin and Yang Deficiency. Conclusion （1）The probability of vascular accident and cerebrovascular accident is higher in liver-fire hyperactivity patients with hypertensive.（2）The sitting systolic pressure of upper arm， sitting diastolic pressure， age， heart rate， and pulse pressure are significant influencing factors on PWV value. 　　[Key words] TCM syndrome type； Hypertension； SBP； PWV 　　高血压病（EH）是以体循环动脉压升高，周围小动脉阻力增高为主要特点的临床综合征，动脉压升高可导致靶器官如心、脑、肾和视网膜的损害而危害人的健康和生命，目前患者的治疗率及控制率较低，仅分别为12.1%和2.8%[1]。利用当前先进的科学技术手段进行高血压病的辨证分型的现代医学研究，建立高血压病的规范化的辨证标准，可以指导高血压的治疗。本研究对高血压病不同中医证型之间脉搏波传导速度（PWV）相关性的研究，以期筛选出高血压病辨证的客观化指标，为高血压病辨证客观化和规范化提供科学依据。 　　1 资料与方法 　　1.1 一般资料 　　收集我