3.0T磁共振全身弥散成像技术初步应用.docVIP

3.0T磁共振全身弥散成像技术初步应用 　　摘要：目的 探讨3.0T磁共振全身弥散成像的技术可行性，并与1.5T磁共振全身弥散成像图像在成像技术及图像质量方面进行比对。方法 于GE 3.0T MR对13例健康志愿者(年龄均为27岁)行全身弥散成像，并于GE ADW4.4，将原始横断位弥散图像经Add/Sub工具进行拼接，得到HD-MIP图像、黑白反转图像及伪彩图像。结果 3.0T MR较1.5T MR的弥散图像具有更好的对比度，但磁敏感导致的图像变形，信号丢失，运动伪影更为严重，图像质量有所降低，段间移位更为明显。结论 3.0TMR有望得到信噪比良好、具有诊断价值的全身弥散图像，但由于磁敏感伪影及错位严重，故尚需要序列的优化、技术的改进以及进一步的临床研究。 　　关键词：磁共振；3.0T ；全身弥散成像 　　Preliminary Application of Whole Body Diffusion-weighted Imaging on 3.0T MR 　　WEI Lai 1,ZHAO Ze-hua1,CHEN Ke-min2,PENG Yi-feng1 　　(1.Department of Radiology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine,Shanghai 200062, China;2.Department of Radiology, Ruijin Hospital, Shanghai Jiaotong University ,Shanghai200062, China) 　　Abstract：ObjectiveTo evaluate preliminary application of WB-DWI (whole body diffusion-weighted imaging) on 3.0T MR. MethodsThe whole body diffusion weighted imaging with background suppression (b＝400 s/mm2) were performed on 3 volunteers (all aged 27).The images were displayed with postprocessed 3D-MIP (3 dimensional -maximum intensity projection) and technique with reverse black and white, pseudo-color. ResultsWB-DWI on 3.0T MR has good image contrast, but both the artifacts and malpositions between different sections are more serious.ConclusionWe can get WBD images with good SNR and diagnostic values on 3.0 MR. But because of the artifacts and malpositions, we still need more clinical researches to improve the technology and optimize the sequence. 　　Key words：Magnetic resonance (MR); 3.0T MR; Whole-body diffusion weighted imaging (WB-DWI）1资料与方法 　　1.1一般资料于2010年3月～4月对13例健康志愿者行3.0T磁共振全身弥散成像，志愿者年龄均为27岁；同时对12例健康志愿者行1.5T磁共振全身弥散成像，志愿者年龄单位为27~40岁。 　　1.2检查仪器与参数 MR扫描：GE Excite HD TwinSpeed 3.0T Signa MR/GE Excite HD TwinSpeed 1.5T Signa MR。自头至膝部以下，横断面分7段扫描，弥散敏感梯度施加的方向为上下，自由呼吸，体线圈接收，ZOOM梯度线圈。采用STIR-DWI扫描技术，DWI-STIR序列扫描参数为：TR:9000ms，TE:55.5ms，矩阵130×128，TI（IR）: 250ms，NEX=4，FOV=40.0cm2，b=0、400s/mm2。FSE序列扫描参数为：TR: 2000ms，TE:85ms，矩阵160×160，FOV=40.0cm2。层厚8mm，全身共分7段扫描，自由呼吸完成，每段弥