不同术式治疗早期胸段食管癌临床疗效及对预后影响.docVIP

不同术式治疗早期胸段食管癌的临床疗效及对预后的影响 　　[摘要]目的 探讨不同术式治疗早期胸段食管癌的临床疗效及对患者预后造成的影响。方法 我院心胸外科2013年1月～2015年12月纳入共50例早期胸段食管癌患者，将其随机分为对照组（28例）和观察组（22例）。对照组行传统开胸手术治疗，观察组胸腹腔镜下食管癌根治术进行治疗，对比两组手术效果及预后差异。结果 观察组具有手术时间短、术中出血量少的优势，与对照组比较，差异有统计学意义（P0.05）。观察组术后KPS、QLQ-C30评分显著高于对照组，差异有统计学意义（P0.05）。结论 早期胸段食管癌患者应用胸腹腔镜下食管癌根治术治疗效果显著，临床预后较好。 　　[关键词]胸段食管癌；早期；传统开胸手术；胸腹腔镜下食管癌根治术；疗效；预后 　　[中图分类号] R735.1 [文献标识码] A [文章编号] 1674-4721（2016）07（b）-0063-03 　　[Abstract]Objective To explore the clinical effects of different operations in treating early stage thoracic esophageal cancer and analyze the impact of different operations on the prognosis of patients.Methods 50 patients with early stage thoracic esophageal cancer in cardio-thoracic surgery of our hospital from January 2013 to December 2015 were selected and randomly divided into control group （28 cases） and observation group （22 cases）.Patients in the control group were given traditional open chest surgery，and patients in the observation group were given radical surgery for esophageal cancer under thoracic laparoscopy.The difference of surgery effects and prognosis in two groups were compared.Results The observation group had the advantages of shorten operation time and less bleeding volume during operation，and the difference was obvious when compared with control group （P0.05）.The postoperative KPS and QLQ-C30 score in the observation group was obviously higher than that in the control group respectively，and the difference was obvious （P0.05）.Conclusion Using radical surgery under thoracic laparoscopy for early stage thoracic esophageal cancer patients has obvious treatment effects and with good clinical prognosis. 　　[Key words]Thoracic esophageal cancer；Early stage；Traditional open chest surgery；Radical surgery for esophageal carcinoma under thoracic laparoscopy；Effects；Prognosis 　　早期食管癌患者通常应用手术切除法治疗，且越早治疗预后越好[1]。传统的开胸手术切除治疗给患者带来了巨大的痛苦，该术式具有创伤大、术中出血量多等缺点，对患者身体造成严重创伤，且术后并发症发生率较高[2]。随着医学技术的不断发展，医学水平、设备等不断的更新改进，临床上推出了非传统开胸手术治疗法，如胸腔镜手术可明显减轻患者的痛苦，具有手术切口减