两种三联疗法治疗幽门螺旋杆菌相关性胃溃疡临床分析.docVIP

两种三联疗法治疗幽门螺旋杆菌相关性胃溃疡的临床分析 　　【摘要】目的：探讨两种三联疗法治疗幽门螺旋杆菌相关性胃溃疡的临床效果。方法：选取2016年2月-2017年5月88例老年幽门螺旋杆菌相关性胃溃疡患者并随机数字表法分组。治疗组采用埃索美拉唑三联疗法进行治疗，对照组组采用奥美拉唑三联疗法进行治疗。比较两组幽门螺旋杆菌相关性胃溃疡转归率；幽门螺旋杆菌根除时间、溃疡愈合时间、治愈时间；干预前后患者红细胞聚集指数、血浆黏度、CRP。结果：治疗组幽门螺旋杆菌相关性胃溃疡转归率高于对照组，P0.05；干预后治疗组红细胞聚集指数、血浆黏度、CRP优于对照组，P0.05。?Y论：两种三联疗法治疗幽门螺旋杆菌相关性胃溃疡的临床效果存在差异，相对于以奥美拉唑为首的三联疗法，埃索美拉唑三联疗法有明显优势，可更好改善病情，缩短疗程和改善血液流变学指标，降低炎症水平，更好根除幽门螺旋杆菌。 　　【关键词】两种三联疗法；幽门螺旋杆菌相关性胃溃疡；临床效果 　　Clinical analysis of two kinds of triple therapy in treatment of Helicobacter pylori associated gastric ulcer 　　Pan Guangheng（Shiti Town Center Health Center， Dachuan District， Sichuan Province， Dazhou Sichuan 635038， China） 　　Abstract Objective： To investigate the clinical effect of two kinds of triple therapy in the treatment of Helicobacter pylori-associated gastric ulcer. Methods ： From February 2016 to May 2017， 88 elderly patients with Helicobacter pylori-associated gastric ulcer were selected and randomly divided into groups. The treatment group was treated with esomeprazole triple therapy， while the control group was treated with omeprazole triple therapy. The rates of H. pylori-associated gastric ulcer were compared between the two groups； H. pylori eradication time， ulcer healing time and healing time； and before and after intervention， erythrocyte aggregation index， plasma viscosity and CRP. Results： The cure rate of Helicobacter pylori-associated gastric ulcer in the treatment group was higher than that in the control group （P 0.05）. After intervention， the erythrocyte aggregation index， plasma viscosity and CRP in the treatment group were better than those in the control group （P 0.05）. Conclusion： The clinical effects of two kinds of triple therapy in the treatment of H. pylori-associated gastric ulcer are different. Compared with the triple therapy including omeprazole， esomeprazole triple therapy has obvious advantages， which can better improve the condition and shorten Treatment and improve blood rheology indicators， reduce th